product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Laminin subunit alpha-2 (LAMA2), partial
catalog :
MBS949425
quantity :
0.5 mg (E-Coli)
price :
1000 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS949425
products type :
Recombinant Protein
products full name :
Recombinant Human Laminin subunit alpha-2 (LAMA2), partial
products short name :
Laminin subunit alpha-2 (LAMA2), partial
products name syn :
Laminin subunit alpha-2; Laminin M chain; Laminin-12 subunit alpha; Laminin-2 subunit alpha; Laminin-4 subunit alpha; Merosin heavy chain
other names :
laminin subunit alpha-2 isoform a; Laminin subunit alpha-2; Laminin M chain; Laminin-12 subunit alpha; Laminin-2 subunit alpha; Laminin-4 subunit alpha; Merosin heavy chain
products gene name :
LAMA2
products gene name syn :
LAMA2; LAMM
other gene names :
LAMA2; LAMM
uniprot entry name :
LAMA2_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
products description :
LAMA2; LAMM
ncbi gi num :
28559088
ncbi acc num :
NP_000417.2
ncbi gb acc num :
NM_000426.3
uniprot acc num :
P24043
ncbi mol weight :
343,905 Da
ncbi pathways :
Alpha6-Beta4 Integrin Signaling Pathway (198807); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Arrhythmogenic Right Ventricular Cardiomyopathy Pathway (672454); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (117293); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (116129); Dilated Cardiomyopathy Pathway (121494); Dilated Cardiomyopathy Pathway (121285); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479)
ncbi summary :
Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
LAMA2: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Defects in LAMA2 are the cause of merosin-deficient congenital muscular dystrophy type 1A (MDC1A). MDC1A is characterized by difficulty walking, hypotonia, proximal weakness, hyporeflexia, and white matter hypodensity on MRI. Protein type: Secreted; Motility/polarity/chemotaxis; Extracellular matrix; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 6q22-q23. Cellular Component: extracellular matrix; laminin-1 complex; extracellular region; dendritic spine; basement membrane; sarcolemma. Molecular Function: structural molecule activity; receptor binding. Biological Process: regulation of cell adhesion; positive regulation of synaptic transmission, cholinergic; axon guidance; extracellular matrix organization and biogenesis; muscle development; regulation of embryonic development; cell adhesion; regulation of cell migration; myelination in the peripheral nervous system. Disease: Muscular Dystrophy, Congenital Merosin-deficient, 1a
size1 :
0.5 mg (E-Coli)
price1 :
1000 USD
size2 :
0.05 mg (Baculovirus)
price2 :
1000
size3 :
0.5 mg (Yeast)
price3 :
1235
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1235
size5 :
1 mg (E-Coli)
price5 :
1510
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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