product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Killer cell immunoglobulin-like receptor 2DL2 (KIR2DL2)
catalog :
MBS949143
quantity :
1 mg (E Coli Derived
price :
1470 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS949143
products type :
Recombinant Protein
products full name :
Recombinant Human Killer cell immunoglobulin-like receptor 2DL2 (KIR2DL2)
products short name :
Killer cell immunoglobulin-like receptor 2DL2 (KIR2DL2)
other names :
killer cell immunoglobulin-like receptor 2DL2; Killer cell immunoglobulin-like receptor 2DL2; killer cell immunoglobulin-like receptor 2DL2; p58 NK receptor CL-43; MHC class I NK cell receptor; CD158 antigen-like family member B1; natural killer-associated transcript 6; p58 natural killer cell receptor clone CL-43; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2; CD158 antigen-like family member B1; MHC class I NK cell receptor; Natural killer-associated transcript 6; NKAT-6; p58 natural killer cell receptor clone CL-43; p58 NK receptor CL-43; CD_antigen: CD158b1
products gene name :
KIR2DL2
other gene names :
KIR2DL2; KIR2DL2; NKAT6; p58.2; CD158b; NKAT-6; CD158B1; CD158B1; NKAT6; NKAT-6; p58 NK receptor CL-43
uniprot entry name :
KI2L2_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
22-245
sequence length :
348
sequence :
HEGVHRKPS LLAHPGRLVK SEETVILQCW SDVRFEHFLL HREGKFKDTL HLIGEHHDGV SKANFSIGPM MQDLAGTYRC YGSVTHSPYQ LSAPSDPLDI VITGLYEKPS LSAQPGPTVL AGESVTLSCS SRSSYDMYHL SREGEAHECR FSAGPKVNGT FQADFPLGPA THGGTYRCFG SFRDSPYEWS NSSDPLLVSV IGNPSNSWPS PTEPSSKTGN PRHLH
purity :
>90%
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info1 :
Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Homo sapiens (Human)
other info2 :
Storage Buffer: Tris-based buffer,50% glycerol. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ncbi gi num :
134304833
ncbi acc num :
NP_055034.2
ncbi gb acc num :
NM_014219.2
uniprot acc num :
P43627
ncbi mol weight :
38,472 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Antigen Processing And Presentation Pathway 83074!!Antigen Processing And Presentation Pathway 485!!DAP12 Interactions Pathway 685549!!Graft-versus-host Disease Pathway 83124!!Graft-versus-host Disease Pathway 536!!Immune System Pathway 106386!!Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway 106413!!Innate Immune System Pathway 106387!!Natural Killer Cell Mediated Cytotoxicity Pathway 83079
ncbi summary :
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]
size :
1 mg (E Coli Derived)
price :
1470 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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