product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Neurotrypsin
catalog :
MBS949101
quantity :
0.01 mg (E-Coli)
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS949101
products type :
Recombinant Protein
products full name :
Recombinant Human Neurotrypsin
products short name :
Neurotrypsin
products name syn :
Leydin; Motopsin; Serine protease 12
other names :
neurotrypsin; Neurotrypsin; neurotrypsin; protease, serine 12; Leydin; Motopsin; Serine protease 12
products gene name :
PRSS12
other gene names :
PRSS12; PRSS12; MRT1; BSSP3; BSSP-3
uniprot entry name :
NETR_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
631-874
sequence length :
875
sequence :
IIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSC
WVLTAAHCFKRYGNSTRSYAVRVGDYHTLVPEEFEEEIG
VQQIVIHREYRPDRSDYDIALVRLQGPEEQCARFSSHVL
PACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAI
PLLPKRFCEERYKGRFTGRMLCAGNLHEHKRVDSCQGDS
GGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSA
FVPWIKSVTK
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info2 :
Species: Homo sapiens (Human)
products categories :
Cell Biology
products description :
Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
products references :
Cloning and sequencing of the cDNA encoding human neurotrypsin." Proba K., Gschwend T.P., Sonderegger P. Biochim. Biophys. Acta 1396:143-147(1998)
ncbi gi num :
300244530
ncbi acc num :
NP_003610.2
ncbi gb acc num :
NM_003619.3
uniprot acc num :
P56730
ncbi mol weight :
43.36kD
ncbi summary :
This gene encodes a member of the trypsin family of serine proteases. Studies in mouse suggest that the encoded enzyme may be involved in structural reorganizations associated with learning and memory. The enzyme is also expressed in Leydig cells in the testis, but its function in this tissue is unknown. Defects in this gene are a cause of mental retardation autosomal recessive type 1 (MRT1). [provided by RefSeq, Jul 2010]
uniprot summary :
PRSS12: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. Defects in PRSS12 are the cause of mental retardation autosomal recessive type 1 (MRT1). Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Belongs to the peptidase S1 family. Protein type: EC 3.4.21.-; Vesicle; Secreted, signal peptide; Protease; Secreted. Chromosomal Location of Human Ortholog: 4q28.1. Cellular Component: axon; cytoplasmic vesicle; dendrite; plasma membrane; terminal button. Molecular Function: scavenger receptor activity; serine-type endopeptidase activity; serine-type peptidase activity. Biological Process: exocytosis; receptor-mediated endocytosis; zymogen activation. Disease: Mental Retardation, Autosomal Recessive 1
size1 :
0.01 mg (E-Coli)
price1 :
140 USD
size2 :
0.05 mg (E-Coli)
price2 :
245
size3 :
0.2 mg (E-Coli)
price3 :
605
size4 :
0.5 mg (E-Coli)
price4 :
990
size5 :
1 mg (E-Coli)
price5 :
1550
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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