catalog number :
MBS949052
products type :
Recombinant Protein
products full name :
Recombinant Rat Glial fibrillary acidic protein (Gfap)
products short name :
Glial fibrillary acidic protein (Gfap)
products name syn :
Glial fibrillary acidic protein; GFAP
other names :
glial fibrillary acidic protein; Glial fibrillary acidic protein; glial fibrillary acidic protein; intermediate filament; glial fibrillary acidic protein alpha; glial fibrillary acidic protein
products gene name :
Gfap
other gene names :
Gfap; Gfap; GFAP
uniprot entry name :
GFAP_RAT
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-430;Full length
sequence :
MERRRITSARRSYASSETMVRGHGPTRHLGTIPRLSLSR
MTPPLPARVDFSLAGALNAGFKETRASERAEMMELNDRF
ASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAE
LRELRLRLDQLTTNSARLEVERDNLTQDLGTLRQKLQDE
TNLRLEAENNLAVYRQEADEATLARVDLERKVESLEEEI
QFLRKIHEEEVRELQEQLAQQQVHVEMDVAKPDLTAALR
EIRTQYEAVATSNMQETEEWYRSKFADLTDVASRNAELL
RQAKHEANDYRRQLQALTCDLESLRGTNESLERQMREQE
ERHARESASYQEALARLEEEGQSLKEEMARHLQEYQDLL
NVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRET
SLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDV
M
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Rattus norvegicus (Rat)
ncbi acc num :
NP_058705.2
ncbi gb acc num :
NM_017009.2
ncbi mol weight :
48,782 Da
ncbi pathways :
Nuclear Signaling By ERBB4 Pathway (530744); Signal Transduction Pathway (477114); Signaling By ERBB4 Pathway (530741)
ncbi summary :
intermediate filament protein specific for astrocytes [RGD, Feb 2006]
uniprot summary :
GFAP: a class-III intermediate filament protein. A cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant isoform has been described, but its full length sequence has not been determined. Protein type: Cytoskeletal. Cellular Component: cell projection; membrane; cytoplasm; intermediate filament; myelin sheath. Molecular Function: integrin binding; structural constituent of cytoskeleton; structural molecule activity; kinase binding. Biological Process: Bergmann glial cell differentiation; extracellular matrix organization and biogenesis; regulation of neurotransmitter uptake; response to wounding; neurite regeneration; intermediate filament organization; intermediate filament-based process; astrocyte development
size2 :
0.05 mg (Baculovirus)
size4 :
0.05 mg (Mammalian-Cell)