catalog number :
MBS948896
products type :
Recombinant Protein
products full name :
Recombinant Human Glycogen debranching enzyme (AGL) ,partial
products short name :
Glycogen debranching enzyme(AGL) ,partial
other names :
glycogen debranching enzyme isoform 1; Glycogen debranching enzyme; glycogen debranching enzyme; glycogen debrancher; amylo-1, 6-glucosidase, 4-alpha-glucanotransferase; amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase; Glycogen debrancherIncluding the following 2 domains:4-alpha-glucanotransferase (EC:2.4.1.25)Alternative name(s):Oligo-1,4-1,4-glucantransferase
other gene names :
AGL; AGL; GDE; GDE; Amylo-1,6-glucosidase
uniprot entry name :
GDE_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
97-253
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info1 :
Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Homo sapiens (Human)
other info2 :
Storage Buffer: Tris-based buffer,50% glycerol. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ncbi acc num :
NP_000019.2
ncbi gb acc num :
NM_000028.2
ncbi mol weight :
172,696 Da
ncbi pathways :
Disease Pathway 530764!!Glucose Metabolism Pathway 106199!!Glycogen Metabolism Pathway 198856!!Glycogen Breakdown (glycogenolysis) Pathway 106212!!Glycogen Storage Diseases Pathway 980468!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Carbohydrates Pathway 106196!!Myoclonic Epilepsy Of Lafora Pathway 980469!!Starch And Sucrose Metabolism Pathway 82974
ncbi summary :
This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
size :
1 mg (E Coli Derived)