product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Rab GDP dissociation inhibitor beta
catalog :
MBS948771
quantity :
0.05 mg (E-Coli)
price :
190 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS948771
products type :
Recombinant Protein
products full name :
Recombinant Human Rab GDP dissociation inhibitor beta
products short name :
Rab GDP dissociation inhibitor beta
products name syn :
Guanosine diphosphate dissociation inhibitor 2; GDI-2
other names :
rab GDP dissociation inhibitor beta isoform 2; Rab GDP dissociation inhibitor beta; rab GDP dissociation inhibitor beta; GDP dissociation inhibitor 2; Guanosine diphosphate dissociation inhibitor 2; GDI-2
products gene name :
GDI2
other gene names :
GDI2; GDI2; RABGDIB; HEL-S-46e; RABGDIB; Rab GDI beta; GDI-2
uniprot entry name :
GDIB_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-445
sequence length :
400
sequence :
MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYY
GGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIP
KFLMANGQLVKMLLYTEVTRYLDFKVTEGSFVYKGGKIY
KVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPR
TFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALALYRTD
DYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGEL
PQGFARLSAIYGGTYMLNKPI
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products description :
Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from th, and the subsequent binding of GTP to th.
products references :
Asada M., Kaibuchi K., Takai Y. The human rab GDI beta gene with long retroposon-rich introns maps to 10p15 and its pseudogene to 7p11-p13.Sedlacek Z., Munstermann E., Mincheva A., Lichter P., Poutska A.Mamm. Genome 9:78-80(1998)
ncbi gi num :
169646441
ncbi acc num :
NP_001108628.1
ncbi gb acc num :
NM_001115156.1
uniprot acc num :
P50395
ncbi mol weight :
52.66kD
ncbi pathways :
Rho GTPase Cycle Pathway (1269508); Signal Transduction Pathway (1269379); Signaling By Rho GTPases Pathway (1269507)
ncbi summary :
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
uniprot summary :
GDI2: Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Belongs to the Rab GDI family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: G protein regulator, misc.; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 10p15. Cellular Component: cytoplasm; cytosol; focal adhesion; Golgi apparatus; membrane; myelin sheath; vesicle. Molecular Function: GTPase activator activity; oxidoreductase activity; protein binding; Rab GDP-dissociation inhibitor activity; small GTPase binding. Biological Process: positive regulation of GTPase activity; protein transport; regulation of small GTPase mediated signal transduction; signal transduction; small GTPase mediated signal transduction; vesicle-mediated transport
size1 :
0.05 mg (E-Coli)
price1 :
190 USD
size2 :
0.2 mg (E-Coli)
price2 :
460
size3 :
0.5 mg (E-Coli)
price3 :
750
size4 :
1 mg (E-Coli)
price4 :
1180
size5 :
0.05 mg (Baculovirus)
price5 :
1225
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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