catalog number :
MBS948435
products type :
Recombinant Protein
products full name :
Recombinant Mouse High affinity immunoglobulin epsilon receptor subunit gamma (Fcer1g)
products short name :
High affinity immunoglobulin epsilon receptor subunit gamma (Fcer1g)
other names :
high affinity immunoglobulin epsilon receptor subunit gamma; High affinity immunoglobulin epsilon receptor subunit gamma; high affinity immunoglobulin epsilon receptor subunit gamma; fceRI gamma; fc-epsilon RI-gamma; Fc receptor gamma-chain; igE Fc receptor subunit gamma; Fc receptor, IgE, high affinity I, gamma polypeptide; Fc receptor gamma-chain; FcRgamma; Fc-epsilon RI-gamma; IgE Fc receptor subunit gamma
products gene name syn :
Recombinant High affinity immunoglobulin epsilon receptor subunit gamma (Fcer1g); High affinity immunoglobulin epsilon receptor subunit gamma; Fc receptor gamma-chain; FcRgamma Fc-epsilon RI-gamma IgE Fc receptor subunit gamma; FceRI gamma
other gene names :
Fcer1g; Fcer1g; CD23; Fce1g; Ly-50; FcR[g]; AI573376; FcRgamma; FcR-gamma; FcepsilonRI; Fce1g; FcRgamma; FceRI gamma
uniprot entry name :
FCERG_MOUSE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
19-23
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Species: Mus musculus (Mouse)
products description :
Fcer1g; Fce1g
ncbi acc num :
NP_034315.1
ncbi gb acc num :
NM_010185.4
ncbi mol weight :
9,652 Da
ncbi pathways :
Asthma Pathway (83313); Asthma Pathway (532); Cell Surface Interactions At The Vascular Wall Pathway (639817); Fc Epsilon RI Signaling Pathway (83279); Fc Epsilon RI Signaling Pathway (493); GPVI-mediated Activation Cascade Pathway (639806); Hemostasis Pathway (639789); Natural Killer Cell Mediated Cytotoxicity Pathway (83276); Natural Killer Cell Mediated Cytotoxicity Pathway (490); Platelet Adhesion To Exposed Collagen Pathway (639798)
uniprot summary :
FCER1G: Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin. Belongs to the CD3Z/FCER1G family. Protein type: Receptor, misc.; Membrane protein, integral. Cellular Component: cell surface; membrane; integral to plasma membrane; Fc-epsilon receptor I complex; integral to membrane; plasma membrane; external side of plasma membrane; lipid raft. Molecular Function: protein binding; transmembrane receptor activity; IgG binding; IgE binding; IgE receptor activity. Biological Process: positive regulation of immune response; antigen processing and presentation of exogenous peptide antigen via MHC class II; signal transduction; mast cell activation; positive regulation of interleukin-10 production; cell surface receptor linked signal transduction; negative regulation of mast cell apoptosis; positive regulation of phagocytosis; antigen processing and presentation of exogenous peptide antigen via MHC class I; Fc receptor mediated stimulatory signaling pathway; integrin-mediated signaling pathway; neutrophil chemotaxis; regulation of immune response; positive regulation of type I hypersensitivity; positive regulation of interleukin-6 production; positive regulation of mast cell degranulation; positive regulation of type III hypersensitivity; positive regulation of tumor necrosis factor production; neutrophil activation during immune response; serotonin secretion by platelet; positive regulation of type IIa hypersensitivity; defense response to bacterium; immunoglobulin mediated immune response; positive regulation of mast cell cytokine production; phagocytosis, engulfment