Recombinant Human 26S proteasome non-ATPase regulatory subunit 7 (PSMD7) | MyBioSource MBS948080 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human 26S proteasome non-ATPase regulatory subunit 7 (PSMD7)

catalog :

MBS948080

quantity :

0.5 mg (E-Coli)

price :

1085 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS948080

products type :

Recombinant Protein

products full name :

Recombinant Human 26S proteasome non-ATPase regulatory subunit 7 (PSMD7)

products short name :

26S proteasome non-ATPase regulatory subunit 7 (PSMD7)

products name syn :

26S proteasome non-ATPase regulatory subunit 7; 26S proteasome regulatory subunit RPN8; 26S proteasome regulatory subunit S12; Mov34 protein homolog; Proteasome subunit p40

other names :

26S proteasome non-ATPase regulatory subunit 7; 26S proteasome non-ATPase regulatory subunit 7; 26S proteasome non-ATPase regulatory subunit 7; Mov34 homolog; proteasome subunit p40; 26S proteasome regulatory subunit S12; 26S proteasome regulatory subunit rpn8; Moloney leukemia virus-34 proviral integration; proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog); proteasome (prosome, macropain) 26S subunit, non-ATPase, 7; 26S proteasome regulatory subunit RPN8; 26S proteasome regulatory subunit S12; Mov34 protein homolog; Proteasome subunit p40

products gene name :

PSMD7

products gene name syn :

PSMD7; MOV34L

other gene names :

PSMD7; PSMD7; P40; S12; Rpn8; MOV34; MOV34L

uniprot entry name :

PSMD7_HUMAN

host :

E Coli or Yeast or Baculovirus or Mammalian Cell

sequence positions :

1-324

sequence length :

324

sequence :

MPELAVQKVV VHPLVLLSVV DHFNRIGKVG NQKRVVGVLL GSWQKKVLDV SNSFAVPFDE DDKDDSVWFL DHDYLENMYG MFKKVNARER IVGWYHTGPK LHKNDIAINE LMKRYCPNSV LVIIDVKPKD LGLPTEAYIS VEEVHDDGTP TSKTFEHVTS EIGAEEAEEV GVEHLLRDIK DTTVGTLSQR ITNQVHGLKG LNSKLLDIRS YLEKVATGKL PINHQIIYQL QDVFNLLPDV SLQEFVKAFY LKTNDQMVVV YLASLIRSVV ALHNLINNKI ANRDAEKKEG QEKEESKKDR KEDKEKDKDK EKSDVKKEEK KEKK

purity :

>90%

form :

Liquid containing glycerol; lyophilization may be available upon request.

storage stability :

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

other info1 :

Species: Homo sapiens (Human)

ncbi gi num :

25777615

ncbi acc num :

NP_002802.2

ncbi gb acc num :

NM_002811.4

uniprot acc num :

P51665

ncbi mol weight :

37,025 Da

ncbi pathways :

APC/C-mediated Degradation Of Cell Cycle Proteins Pathway (105825); APC/C:Cdc20 Mediated Degradation Of Securin Pathway (105833); APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway (105831); APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway (105835); Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway (105829); Activation Of NF-kappaB In B Cells Pathway (576251); Adaptive Immune System Pathway (366160); Antigen Processing-Cross Presentation Pathway (477122); Antigen Processing: Ubiquitination Proteasome Degradation Pathway (366162); Apoptosis Pathway (105648)

ncbi summary :

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2008]

uniprot summary :

PSMD7: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Belongs to the peptidase M67A family. Protein type: Proteasome complex; Protease. Chromosomal Location of Human Ortholog: 16q22.3. Cellular Component: proteasome complex; nucleoplasm; membrane; proteasome regulatory particle; cytosol; nucleus. Molecular Function: protein binding; protein homodimerization activity. Biological Process: positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; protein polyubiquitination; viral reproduction; apoptosis; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; regulation of apoptosis; antigen processing and presentation of peptide antigen via MHC class I; regulation of ubiquitin-protein ligase activity during mitotic cell cycle; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; gene expression; mitotic cell cycle; regulation of amino acid metabolic process; G1/S transition of mitotic cell cycle; negative regulation of apoptosis

size1 :

0.5 mg (E-Coli)

price1 :

1085 USD

size2 :

0.05 mg (Baculovirus)

price2 :

1085

size3 :

0.5 mg (Yeast)

price3 :

1315

size4 :

0.05 mg (Mammalian-Cell)

price4 :

1315

size5 :

1 mg (E-Coli)

price5 :

1705

more info or order :

MyBioSource product webpage