product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Loricrin (LOR)
catalog :
MBS947887
quantity :
0.5 mg (E-Coli)
price :
1070 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS947887
products type :
Recombinant Protein
products full name :
Recombinant Human Loricrin (LOR)
products short name :
Loricrin (LOR)
products name syn :
Loricrin
other names :
loricrin; Loricrin; loricrin; loricrin
products gene name :
LOR
products gene name syn :
LOR; LRN
other gene names :
LOR; LOR; LRN
uniprot entry name :
LORI_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-312
sequence length :
312
sequence :
MSYQKKQPTP QPPVDCVKTS GGGGGGGGSG GGGCGFFGGG GSGGGSSGSG CGYSGGGGYS GGGCGGGSSG GGGGGGIGGC GGGSGGSVKY SGGGGSSGGG SGCFSSGGGG SGCFSSGGGG SSGGGSGCFS SGGGGSSGGG SGCFSSGGGG FSGQAVQCQS YGGVSSGGSS GGGSGCFSSG GGGGSVCGYS GGGSGCGGGS SGGSGSGYVS SQQVTQTSCA PQPSYGGGSS GGGGSGGSGC FSSGGGGGSS GCGGGSSGIG SGCIISGGGS VCGGGSSGGG GGGSSVGGSG SGKGVPICHQ TQQKQAPTWP SK
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
products description :
Major keratinocyte cell envelope protein.
ncbi gi num :
109255251
ncbi acc num :
NP_000418.2
ncbi gb acc num :
NM_000427.2
uniprot acc num :
P23490
ncbi mol weight :
49kD
ncbi summary :
This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases. [provided by RefSeq, Jul 2008]
uniprot summary :
LOR: Major keratinocyte cell envelope protein. Defects in LOR are a cause of progressive symmetric erythrokeratodermia (PSEK). Erythrokeratodermas are a group of disorders characterized by widespread erythematous plaques, either stationary or migratory, associated with features that include palmoplantar keratoderma. PSEK is characterized by erythematous and hyperkeratotic plaques. Defects in LOR are the cause of Vohwinkel syndrome with ichthyosis (VSI); also known as loricrin keratoderma (LK) or mutilating keratoderma with ichthyosis. VSI is an ichthyotic variant of Vohwinkel syndrome (VS) characterized by progressive symmetric erythrokeratoderma or congenital ichthyosiform erythroderma born as a collodion baby. Common clinical features include hyperkeratosis of the palms and soles with digital constriction. Chromosomal Location of Human Ortholog: 1q21. Cellular Component: nucleoplasm; cytoplasm; cornified envelope. Molecular Function: protein binding, bridging; protein binding; structural constituent of cytoskeleton; structural molecule activity. Biological Process: keratinocyte differentiation; keratinization; peptide cross-linking. Disease: Vohwinkel Syndrome, Variant Form
size1 :
0.5 mg (E-Coli)
price1 :
1070 USD
size2 :
0.05 mg (Baculovirus)
price2 :
1070
size3 :
0.5 mg (Yeast)
price3 :
1300
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1300
size5 :
1 mg (E-Coli)
price5 :
1675
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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