Human A disintegrin and metalloproteinase with thrombospondin motifs 7, ADAMTS7 ELISA Kit | MyBioSource MBS947357 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human A disintegrin and metalloproteinase with thrombospondin motifs 7, ADAMTS7 ELISA Kit

catalog :

MBS947357

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS947357

products type :

ELISA Kit

products full name :

Human A disintegrin and metalloproteinase with thrombospondin motifs 7, ADAMTS7 ELISA Kit

products short name :

ADAM metallopeptidase with thrombospondin type 1 motif, 7

products name syn :

Human A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAMTS7) ELISA kit; ADAM-TS7; DKFZp434H204; COMPase; a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif; ADAM metallopeptidase with thrombospondin type 1 motif; 7

other names :

A disintegrin and metalloproteinase with thrombospondin motifs 7 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 7; A disintegrin and metalloproteinase with thrombospondin motifs 7; COMPase; a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7; ADAM metallopeptidase with thrombospondin type 1 motif, 7; COMPase

products gene name :

ADAMTS7

other gene names :

ADAMTS7; ADAMTS7; ADAM-TS7; ADAMTS-7; ADAM-TS 7; ADAM-TS 7; ADAM-TS7; ADAMTS-7

uniprot entry name :

ATS7_HUMAN

reactivity :

Human

sequence length :

1686

specificity :

This assay has high sensitivity and excellent specificity for detection of human ADAMTS7. No significant cross-reactivity or interference between human ADAMTS7 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 3.12 ng/ml -200 ng/ml. Sensitivity: The minimum detectable dose of human ADAMTS7 is typically less than 0.78 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ADAMTS7 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ADAMTS7 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ADAMTS7 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ADAMTS7 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

38683827

ncbi acc num :

NP_055087.2

ncbi gb acc num :

NM_014272.3

uniprot acc num :

Q9UKP4

ncbi mol weight :

184,095 Da

ncbi summary :

The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two C-terminal TS motifs. [provided by RefSeq, Jul 2008]

uniprot summary :

ADAMTS7: Metalloprotease that may play a role in the degradation of COMP. Protein type: Protease; Motility/polarity/chemotaxis; Secreted, signal peptide; Cell surface; EC 3.4.24.-; Secreted. Chromosomal Location of Human Ortholog: 15q24.2. Cellular Component: proteinaceous extracellular matrix; cell surface; endoplasmic reticulum lumen. Molecular Function: protein binding; metallopeptidase activity; zinc ion binding; metalloendopeptidase activity. Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; proteolysis involved in cellular protein catabolic process; negative regulation of chondrocyte differentiation; post-translational protein modification

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage