Mouse Interleukin 29, IL-29 ELISA Kit | MyBioSource MBS945577 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Interleukin 29, IL-29 ELISA Kit

catalog :

MBS945577

quantity :

24-Strip-Wells (LIMIT 1)

price :

240 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS945577

products type :

ELISA Kit

products full name :

Mouse Interleukin 29, IL-29 ELISA Kit

products short name :

[Interleukin 29 (IL-29)]

products name syn :

[Mouse Interleukin 29 (IL-29) ELISA Kit; IFNL1; IL-29; interferon; lambda 1; interleukin 29; Interleukin 29 (IL-29)]

other names :

[interferon lambda-1; Interferon lambda-1; interferon lambda-1; IFN-lambda-1; interleukin-29; cytokine Zcyto21; interferon-lambda-1; interleukin 29 (interferon, lambda 1); interferon, lambda 1; Cytokine Zcyto21; Interleukin-29; IL-29]

products gene name :

[IL29]

other gene names :

[IFNL1; IFNL1; IL29; IL-29; IL29; ZCYTO21; IFN-lambda-1; IL-29]

uniprot entry name :

IFNL1_HUMAN

reactivity :

Mouse

sequence length :

200

specificity :

This assay has high sensitivity and excellent specificity for detection of mouse IL-29. No significant cross-reactivity or interference between mouse IL-29 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Quantitative Sandwich. Sensitivity: Typically less than 3.1 pg/ml.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IL-29 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL-29 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL-29 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL-29 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

26024325

ncbi acc num :

NP_742152.1

ncbi gb acc num :

NM_172140.1

uniprot acc num :

Q8IU54

ncbi mol weight :

21,898 Da

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488)

ncbi summary :

This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]

uniprot summary :

IL29: Cytokine with immunomodulatory activity. May play a role in antiviral immunity. Up-regulates MHC class I antigen expression. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Belongs to the IL-28/IL-29 family. Protein type: Secreted, signal peptide; Cell cycle regulation; Secreted; Cytokine. Chromosomal Location of Human Ortholog: 19q13.13. Cellular Component: extracellular space; extracellular region; interleukin-28 receptor complex. Molecular Function: cytokine activity; interleukin-28 receptor binding; receptor binding. Biological Process: positive regulation of immune response; positive regulation of transcription, DNA-dependent; positive regulation of JAK-STAT cascade; JAK-STAT cascade; negative regulation of T cell differentiation; negative regulation of cell proliferation; positive regulation of interferon-gamma production; negative regulation of interleukin-13 production; negative regulation of T-helper 2 type immune response; positive regulation of tyrosine phosphorylation of STAT protein; negative regulation of interleukin-5 production; positive regulation of MHC class I biosynthetic process; negative regulation of transcription, DNA-dependent; negative regulation of memory T cell differentiation; defense response to virus

size1 :

24-Strip-Wells (LIMIT 1)

price1 :

240 USD

size2 :

48-Strip-Wells

price2 :

495

size3 :

96-Strip-Wells

price3 :

710

size4 :

5x96-Strip-Wells

price4 :

2705

size5 :

10x96-Strip-Wells

price5 :

5145

more info or order :

MyBioSource product webpage