catalog number :
MBS945200
products type :
ELISA Kit
products full name :
Mouse Tumor necrosis factor receptor superfamily member 3, LTBR ELISA Kit
products short name :
lymphotoxin beta receptor (TNFR superfamily, member 3)
products name syn :
Mouse Tumor necrosis factor receptor superfamily member 3 (LTBR) ELISA kit; CD18; D12S370; LT-BETA-R; TNF-R-III; TNFCR; TNFR-RP; TNFR2-RP; TNFRSF3; TNFR superfamily; member 3; lymphotoxin B receptor; lymphotoxin beta receptor; tumor necrosis factor C receptor; tumor necrosis fa; lymphotoxin beta receptor (TNFR superfamily; member 3)
other names :
tumor necrosis factor receptor superfamily member 3; Tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor superfamily member 3; LT beta-R; LT-beta receptor; lymphotoxin-beta receptor; TNF receptor-related protein; tumor necrosis factor receptor superfamily, member 3; lymphotoxin B receptor; Lymphotoxin-beta receptor
products gene name :
LTBR
other gene names :
Ltbr; Ltbr; CD18; Ltar; TNFCR; Tnfbr; TNFRrp; LTbetaR; TNFR-RP; Tnfrsf3; AI256028; TNFR2-RP; TNF-R-III; Tnfcr; Tnfrsf3
uniprot entry name :
TNR3_MOUSE
specificity :
This assay has high sensitivity and excellent specificity for detection of mouse LTBR. No significant cross-reactivity or interference between mouse LTBR and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 31.2 pg/ml-2000 pg/ml. Sensitivity: Typically less than 7.8 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for LTBR has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any LTBR present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for LTBR is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of LTBR bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_034866.1
ncbi gb acc num :
NM_010736.3
ncbi mol weight :
44,956 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); HTLV-I Infection Pathway (373903); HTLV-I Infection Pathway (373889); Intestinal Immune Network For IgA Production Pathway (128761); Intestinal Immune Network For IgA Production Pathway (128670); NF-kappa B Signaling Pathway (634537)
uniprot summary :
LTBR: Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. Protein type: Membrane protein, integral. Cellular Component: membrane; integral to membrane. Molecular Function: identical protein binding; protein binding; ubiquitin protein ligase binding. Biological Process: apoptosis; positive regulation of JNK cascade; myeloid dendritic cell differentiation; lymph node development
size4 :
10x96-Strip-Wells