Human Bone morphogenetic protein 8B, BMP8B ELISA Kit | MyBioSource MBS944757 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Bone morphogenetic protein 8B, BMP8B ELISA Kit

catalog :

MBS944757

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS944757

products type :

ELISA Kit

products full name :

Human Bone morphogenetic protein 8B, BMP8B ELISA Kit

products short name :

bone morphogenetic protein 8b

products name syn :

Human Bone morphogenetic protein 8B (BMP8B) ELISA kit; BMP8; MGC131757; OP2; bone morphogenetic protein 8 (osteogenic protein 2) ; bone morphogenetic protein 8B; dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2) ) ; osteogenic protein 2; bone morphogenetic protein 8b

other names :

bone morphogenetic protein 8B preproprotein; Bone morphogenetic protein 8B; bone morphogenetic protein 8B; BMP-8; BMP-8B; osteogenic protein 2; bone morphogenetic protein 8 (osteogenic protein 2); dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)); bone morphogenetic protein 8b; Osteogenic protein 2; OP-2

products gene name :

BMP8B

other gene names :

BMP8B; BMP8B; OP2; BMP8; BMP8; BMP-8; BMP-8B; OP-2

uniprot entry name :

BMP8B_HUMAN

reactivity :

Human

sequence length :

402

specificity :

This assay has high sensitivity and excellent specificity for detection of human BMP8B. No significant cross-reactivity or interference between human BMP8B and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Quantitative Sandwich. Sensitivity: Typically less than 2.34 pg/ml.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for BMP8B has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any BMP8B present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for BMP8B is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of BMP8B bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

29571106

ncbi acc num :

NP_001711.2

ncbi gb acc num :

NM_001720.3

uniprot acc num :

P34820

ncbi mol weight :

44,768 Da

ncbi pathways :

Hedgehog Signaling Pathway (83063); Hedgehog Signaling Pathway (474); TGF-beta Signaling Pathway (83064); TGF-beta Signaling Pathway (475)

ncbi summary :

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008]

uniprot summary :

BMP8B: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Belongs to the TGF-beta family. Protein type: Cytokine; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1p35-p32. Cellular Component: extracellular space. Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding. Biological Process: regulation of apoptosis; BMP signaling pathway; ossification; regulation of MAPKKK cascade; cartilage development; skeletal development; cell development; growth

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage