Mouse Apolipoprotein C-III, APOC3 ELISA Kit | MyBioSource MBS944394 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Apolipoprotein C-III, APOC3 ELISA Kit

catalog :

MBS944394

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

citations: 1

Reference
Cheng X, Yamauchi J, Lee S, Zhang T, Gong Z, Muzumdar R, et al. APOC3 Protein Is Not a Predisposing Factor for Fat-induced Nonalcoholic Fatty Liver Disease in Mice. J Biol Chem. 2017;292:3692-3705 pubmed publisher

product information

catalog number :

MBS944394

products type :

ELISA Kit

products full name :

Mouse Apolipoprotein C-III, APOC3 ELISA Kit

products short name :

apolipoprotein C-III

products name syn :

Mouse Apolipoprotein C-III (APOC3) ELISA kit; APOCIII; MGC150353; ; apolipoprotein C-III

other names :

apolipoprotein C-III isoform b; Apolipoprotein C-III; apolipoprotein C-III; apolipoprotein C3; apolipoprotein C-III; Apolipoprotein C3

products gene name :

APOC3

other gene names :

Apoc3; Apoc3; apo-CIII; apoC-III; Apo-CIII; ApoC-III

uniprot entry name :

APOC3_MOUSE

reactivity :

Mouse

sequence length :

specificity :

This assay has high sensitivity and excellent specificity for detection of mouse APOC3. No significant cross-reactivity or interference between mouse APOC3 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Competitive. Detection Range: 18.75 ng/ml -1200 ng/ml. Sensitivity: 9.375 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with APOC3. Standards or samples are added to the appropriate microtiter plate wells with Horseradish Peroxidase (HRP) conjugated antibody preparation specific for APOC3. The competitive inhibition reaction is launched between with pre-coated APOC3 and APOC3 in samples. A substrate solution is added to the wells and the color develops in opposite to the amount of APOC3 in the sample. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

577019554

ncbi acc num :

NP_001276685.1

ncbi gb acc num :

NM_001289756.1

uniprot acc num :

P33622

ncbi mol weight :

10,982 Da

ncbi pathways :

PPAR (Peroxisome Proliferator-activated Receptor) Signaling Pathway (522983); PPAR Signaling Pathway (83239); PPAR Signaling Pathway (450); Statin Pathway (198363)

ncbi summary :

This gene encodes an apolipoprotein which is the major protein component of very-low-density lipoproteins (VLDL) and a minor component of high-density lipoproteins (HDL). The encoded protein is thought to regulate the metabolism of triglyceride-rich lipoproteins and play a role in lipid storage and the mobilization of fat cells. This gene is clustered with three other apolipoprotein genes on chromosome 9 and is associated with coronary disease. Mice lacking this gene have lower levels of total cholesterol in the plasma. Mutations in the human genes causes hyperalphalipoproteinemia 2, a disorder of lipid metabolism which results in a favorable lipid profile (lower LDL-cholesterol, higher HDL-cholesterol and lower levels of serum triglycerides when fasting and after a meal). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

uniprot summary :

APOC3: Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles. Defects in APOC3 are the cause of hyperalphalipoproteinemia type 2 (HALP2). HALP2 is a condition characterized by high levels of high density lipoprotein (HDL) and increased HDL cholesterol levels. Belongs to the apolipoprotein C3 family. Protein type: Lipid-binding; Secreted; Secreted, signal peptide. Cellular Component: extracellular space; chylomicron; cell; extracellular region. Molecular Function: lipid binding. Biological Process: response to peptide hormone stimulus; cholesterol metabolic process; triacylglycerol metabolic process; lipoprotein transport; transport; triacylglycerol catabolic process; lipoprotein metabolic process; lipid metabolic process; triacylglycerol mobilization; lipid transport; lipid catabolic process

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage