ELISA/assay

Human Galectin-3-binding protein, LGALS3BP ELISA Kit

MBS943693

48-Strip-Wells

510 USD

ELISA Kit

Human Galectin-3-binding protein, LGALS3BP ELISA Kit

lectin, galactoside-binding, soluble, 3 binding protein

Human Galectin-3-binding protein (LGALS3BP) ELISA kit; 90K; BTBD17B; MAC-2-BP; L3 antigen; Mac-2-binding protein; galectin 3 binding protein; serum protein 90K; lectin; galactoside-binding; soluble; 3 binding protein

galectin-3-binding protein; Galectin-3-binding protein; galectin-3-binding protein; MAC2BP; mac-2 BP; L3 antigen; serum protein 90K; Mac-2-binding protein; tumor-associated antigen 90K; basement membrane autoantigen p105; transport and golgi organization 10 homolog B; lectin galactoside-binding soluble 3-binding protein; lectin, galactoside-binding, soluble, 3 binding protein; Basement membrane autoantigen p105; Lectin galactoside-binding soluble 3-binding protein; Mac-2-binding protein; MAC2BP; Mac-2 BP; Tumor-associated antigen 90K

LGALS3BP

LGALS3BP; LGALS3BP; 90K; M2BP; gp90; CyCAP; BTBD17B; MAC-2-BP; TANGO10B; M2BP; MAC2BP; Mac-2 BP

LG3BP_HUMAN

Human

585

This assay has high sensitivity and excellent specificity for detection of Human LGALS3BP. No significant cross-reactivity or interference between Human LGALS3BP and analogues was observed.

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 1.56 ng/ml-100 ng/ml. Sensitivity: 0.39 ng/ml

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Cell Adhesion. Protein Biological Process 3: Cell adhesion

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for LGALS3BP has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any LGALS3BP present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for LGALS3BP is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of LGALS3BP bound in the initial step. The color development is stopped and the intensity of the color is measured.

5031863

NP_005558.1

NM_005567.3

Q08380

65,331 Da

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]

LGALS3BP: Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 17q25. Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; membrane. Molecular Function: scavenger receptor activity. Biological Process: receptor-mediated endocytosis; cellular defense response; signal transduction; cell adhesion

48-Strip-Wells

510 USD

96-Strip-Wells

725

5x96-Strip-Wells

2565

10x96-Strip-Wells

4800