catalog number :
MBS943660
products type :
ELISA Kit
products full name :
Human Carcinoembryonic antigen-related cell adhesion molecule 6, CEACAM6 ELISA Kit
products short name :
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
products name syn :
Human Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) ELISA kit; CD66c; CEAL; NCA; carcinoembryonic antigen-related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
other names :
carcinoembryonic antigen-related cell adhesion molecule 6 preproprotein; Carcinoembryonic antigen-related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 6; normal cross-reacting antigen; Cluster of Differentiation 66c; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); Non-specific crossreacting antigen; Normal cross-reacting antigen; CD_antigen: CD66c
products gene name :
CEACAM6
other gene names :
CEACAM6; CEACAM6; NCA; CEAL; CD66c; NCA
uniprot entry name :
CEAM6_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of human CEACAM6. No significant cross-reactivity or interference between human CEACAM6 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 0.83 ng/ml -20 ng/ml. Sensitivity: The minimum detectable dose of human CEACAM6 is typically less than 0.33 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest human CEACAM6 concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<10%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<15%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CEACAM6 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells with a Horseradish Peroxidase (HRP) conjugated antibody specific for CEACAM6. Following a wash to remove any unbound reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CEACAM6 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_002474.4
ncbi gb acc num :
NM_002483.6
ncbi mol weight :
37,195 Da
ncbi summary :
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]
uniprot summary :
CEACAM6: Belongs to the immunoglobulin superfamily. CEA family. Protein type: Membrane protein, GPI anchor; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19q13.2. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: protein binding. Biological Process: cell-cell signaling; signal transduction; blood coagulation; leukocyte migration
size4 :
10x96-Strip-Wells