Human Ecto-NOX disulfide-thiol exchanger 2, ENOX2 ELISA Kit | MyBioSource MBS943476 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Ecto-NOX disulfide-thiol exchanger 2, ENOX2 ELISA Kit

catalog :

MBS943476

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS943476

products type :

ELISA Kit

products full name :

Human Ecto-NOX disulfide-thiol exchanger 2, ENOX2 ELISA Kit

products short name :

ecto-NOX disulfide-thiol exchanger 2

products name syn :

Human Ecto-NOX disulfide-thiol exchanger 2 (ENOX2) ELISA kit; RP5-875H3.1; APK1; COVA1; tNOX; APK1 antigen; OTTHUMP00000024021; OTTHUMP00000024022; cytosolic ovarian carcinoma antigen 1; ecto-NOX disulfide-thiol exchanger 2

other names :

ecto-NOX disulfide-thiol exchanger 2 isoform a; Ecto-NOX disulfide-thiol exchanger 2; ecto-NOX disulfide-thiol exchanger 2; APK1 antigen; cytosolic ovarian carcinoma antigen 1; tumor-associated hydroquinone oxidase; ecto-NOX disulfide-thiol exchanger 2; APK1 antigen; Cytosolic ovarian carcinoma antigen 1; Tumor-associated hydroquinone oxidase; tNOX

products gene name :

ENOX2

other gene names :

ENOX2; ENOX2; APK1; tNOX; COVA1; COVA1; tNOX

uniprot entry name :

ENOX2_HUMAN

reactivity :

Human

sequence length :

610

specificity :

This assay has high sensitivity and excellent specificity for detection of human ENOX2. No significant cross-reactivity or interference between human ENOX2 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates, cell lysates. Assay Type: Sandwich. Detection Range: 31.25 pg/ml-2000 pg/ml. Sensitivity: Typically less than 7.81 pg/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ENOX2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ENOX2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ENOX2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ENOX2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

528524612

ncbi acc num :

NP_001268665.1

ncbi gb acc num :

NM_001281736.1

uniprot acc num :

Q16206

ncbi mol weight :

70,082 Da

ncbi summary :

This gene is a tumor-specific member of the ECTO-NOX family of genes that encode cell surface NADH oxidases. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The protein also displays prion-like properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

uniprot summary :

ENOX2: May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide- thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock. Belongs to the ENOX family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Oxidoreductase; EC 1.-.-.-; Cytoskeletal; Cell surface. Chromosomal Location of Human Ortholog: Xq25. Cellular Component: extracellular space; cytosol; external side of plasma membrane. Molecular Function: nucleic acid binding; nucleotide binding; protein disulfide oxidoreductase activity. Biological Process: regulation of growth; cell growth; ultradian rhythm

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage