product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Interleukin-17 receptor D, IL17RD ELISA Kit
catalog :
MBS943113
quantity :
48-Strip-Wells
price :
510 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS943113
products type :
ELISA Kit
products full name :
Human Interleukin-17 receptor D, IL17RD ELISA Kit
products short name :
interleukin 17 receptor D
products name syn :
Human Interleukin-17 receptor D (IL17RD) ELISA kit; DKFZp434N1928; FLJ35755; IL-17RD; IL17RLM; MGC133309; SEF; ; interleukin 17 receptor D
other names :
interleukin-17 receptor D; Interleukin-17 receptor D; interleukin-17 receptor D; hSef; IL17Rhom; sef homolog; IL-17 receptor D; interleukin-17 receptor-like protein; interleukin 17 receptor D; IL17Rhom; Interleukin-17 receptor-like protein; Sef homolog; hSef
products gene name :
IL17RD
other gene names :
IL17RD; IL17RD; SEF; HH18; IL-17RD; IL17RLM; IL17RLM; SEF; UNQ6115/PRO20026; IL-17 receptor D; IL-17RD; hSef
uniprot entry name :
I17RD_HUMAN
reactivity :
Human
sequence length :
739
specificity :
This assay has high sensitivity and excellent specificity for detection of Human IL17RD. No significant cross-reactivity or interference between Human IL17RD and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 25 pg/ml-1600 pg/ml. Sensitivity: 6.25 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul
products description :
For Sample For the quantitative determination of human interleukin-17 receptor D (IL17RD) concentrations in serum, plasma, tissue homogenates. PRINCIPLE OF THE ASSAY This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IL17RD has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL17RD present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL17RD is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL17RD bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
166063983
ncbi acc num :
NP_060033.3
ncbi gb acc num :
NM_017563.3
uniprot acc num :
Q8NFM7
ncbi mol weight :
82,411 Da
ncbi pathways :
FGF Signaling Pathway (137989); Signal Transduction Pathway (477114); Signaling By FGFR Pathway (106343)
ncbi summary :
This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin (PMID: 19079364). The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling (PMID: 21663947, 18096367). [provided by RefSeq, Nov 2011]
uniprot summary :
IL17RD: Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 3p14.3. Cellular Component: nucleoplasm; Golgi membrane; Golgi apparatus; integral to plasma membrane. Molecular Function: interleukin-17 receptor activity. Biological Process: cytokine and chemokine mediated signaling pathway. Disease: Hypogonadotropic Hypogonadism 18 With Or Without Anosmia
size1 :
48-Strip-Wells
price1 :
510 USD
size2 :
96-Strip-Wells
price2 :
725
size3 :
5x96-Strip-Wells
price3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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