product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
CLPX Antibody
catalog :
MBS9429665
quantity :
0.1 mL
price :
255 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Gel: 8%SDS-PAGE lysate: 40 ¦Œg, Lane: 293T cell lysate, Primary antibody: 46518£¨CLPX Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
image 2 :
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46518(CLPX Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
image 3 :
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 46518(CLPX Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
product information
catalog number :
MBS9429665
products type :
Antibody
products full name :
CLPX Antibody
products short name :
[CLPX]
other names :
[ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial; ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial; ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial; caseinolytic mitochondrial matrix peptidase chaperone subunit]
products gene name :
[CLPX]
other gene names :
[CLPX; CLPX]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
633
specificity :
The antibody detects endogenous levels of total CLPX protein.
purity :
Antigen affinity purification
form :
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
concentration :
0.6mg/ml
storage stability :
Store at -20 degree C.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:200-1:1000. IHC: 1: 20-100
image1 heading :
SDS-Page
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Synthetic peptide corresponding to residues near the C terminal of human CLPX. Immunogen Type: Peptide
products categories :
Total protein Ab
products description :
The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.
ncbi gi num :
7242140
ncbi acc num :
NP_006651
ncbi gb acc num :
NM_006660.4
uniprot acc num :
O76031
ncbi mol weight :
69 kDa
ncbi summary :
The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015]
uniprot summary :
ATP-dependent specificity component of the Clp protease complex. Hydrolyzes ATP. Targets specific substrates for degradation by the Clp complex (PubMed:11923310, PubMed:22710082). Can perform chaperone functions in the absence of CLPP. Enhances the DNA-binding activity of TFAM and is required for maintaining a normal mitochondrial nucleoid structure (PubMed:22841477). ATP-dependent unfoldase that stimulates the incorporation of the pyridoxal phosphate cofactor into 5-aminolevulinate synthase, thereby activating 5-aminolevulinate (ALA) synthesis, the first step in heme biosynthesis. Important for efficient erythropoiesis through upregulation of heme biosynthesis (PubMed:25957689).
size1 :
0.1 mL
price1 :
255 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!
browse more products
questions and comments