catalog number :
MBS9427713
products type :
ELISA Kit
products full name :
Human Alpha-1-antitrypsin ELISA Kit
products short name :
[Alpha-1-antitrypsin]
products name syn :
[Alpha-1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1; SERPINA1; AAT; PI; PRO0684; PRO2209]
other names :
[alpha-1-antitrypsin; Alpha-1-antitrypsin; alpha-1-antitrypsin; serpin family A member 1; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1]
products gene name :
[SERPINA1]
other gene names :
[SERPINA1; SERPINA1; PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT; AAT; PI; SPAAT]
storage stability :
Store at 4 degree C
other info1 :
Samples: Serum, plasma, tissue homogenates and other biological fluids. Detection Range: 3.12-200 ng/mL. Sensitivity: Less than 1.2ng/mL
other info2 :
Assay Time: 3-5h. Sample Volume: 100T. Detection Wavelength: 450 nm.
ncbi acc num :
NP_000286.3
ncbi gb acc num :
NM_000295.4
ncbi mol weight :
34,755 Da
ncbi pathways :
Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); FOXA1 Transcription Factor Network Pathway (137979); Hemostasis Pathway (106028); Platelet Activation, Signaling And Aggregation Pathway (106034); Platelet Degranulation Pathway (106050); Response To Elevated Platelet Cytosolic Ca2+ Pathway (106048)
ncbi summary :
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.