catalog number :
MBS9424336
products type :
Recombinant Protein
products full name :
Recombinant Mouse Enteropeptidase (Tmprss15), partial
products short name :
[Enteropeptidase]
products name syn :
[Enterokinase, Serine protease 7, Transmembrane protease serine 15, Cleaved into the following 2 chains:Enteropeptidase non-catalytic heavy chain,Enteropeptidase catalytic light chain]
other names :
[enteropeptidase isoform 1; Enteropeptidase; enteropeptidase; transmembrane protease, serine 15; Enterokinase; Serine protease 7; Transmembrane protease serine 15]
products gene name :
[Tmprss15]
other gene names :
[Tmprss15; Tmprss15; Entk; Prss7; Entk; Prss7]
sequence positions :
[Expression Region:830-1069aaSequence Info:Partial]
sequence :
IVGGSDAQAGAWPWVVALYHRDRSTDRLLCGASLVSSDW
LVSAAHCVYRRNLDPTRWTAVLGLHMQSNLTSPQVVRRV
VDQIVINPHYDRRRKVNDIAMMHLEFKVNYTDYIQPICL
PEENQIFIPGRTCSIAGWGYDKINAGSTVDVLKEADVPL
ISNEKCQQQLPEYNITESMICAGYEEGGIDSCQGDSGGP
LMCQENNRWFLVGVTSFGVQCALPNHPGVYVRVSQFIEW
IHSFLH
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Tris-based buffer, 50% glycerol
storage stability :
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability
of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C,-80°C. The shelf life of lyophilized form is 12 months at -20°C,-80°C. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for
up to one week
other info1 :
Calculated MW: 43 kDa
other info2 :
Tag Info: N-terminal 6xHis-SUMO-tagged
products description :
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
ncbi acc num :
NP_032967.1
ncbi gb acc num :
NM_008941.3
ncbi summary :
This gene encodes an enzyme that proteolytically activates the pancreatic proenzyme trypsinogen, converting it into trypsin. The encoded protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]
uniprot summary :
PRSS7: Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases. Defects in TMPRSS15 are a cause of enterokinase deficiency (ENTKD); a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive. Belongs to the peptidase S1 family. Protein type: EC 3.4.21.9; Membrane protein, integral; Protease. Chromosomal Location of Human Ortholog: 16 16 C3.1-C3.2