product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Mouse Methylmalonyl-CoA mutase, mitochondrial (Mutc)
catalog :
MBS9424015
quantity :
0.01 mg
price :
265 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS9424015 image 1
product information
catalog number :
MBS9424015
products type :
Recombinant Protein
products full name :
Recombinant Mouse Methylmalonyl-CoA mutase, mitochondrial (Mutc)
products short name :
[Methylmalonyl-CoA mutase, mitochondrial (Mutc)]
products name syn :
[Methylmalonyl-CoA isomerase; Mut]
other names :
[methylmalonyl-CoA mutase, mitochondrial; Methylmalonyl-CoA mutase, mitochondrial; methylmalonyl-CoA mutase, mitochondrial; methylmalonyl-Coenzyme A mutase; Methylmalonyl-CoA isomerase]
products gene name :
[Mutc]
other gene names :
[Mut; Mut; Mcm; D230010K02Rik; MCM]
host :
E Coli
reactivity :
Mouse
sequence positions :
[Full Length, 31-748aa]
sequence :
LHQQQPLHPEWAVLAKKQLKGKNPEDLIWHTPEGISIKP
LYSRADTLDLPEELPGVKPFTRGPYPTMYTYRPWTIRQY
AGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSD
NPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTM
NGAVIPVLATFIVTGEEQGVPKEKLTGTIQNDILKEFMV
RNTYIFPPEPSMKIIADIFQYTAQHMPKFNSISISGYHM
QEAGADAILELAYTIADGLEYCRTGLQAGLTIDEFAPRL
SFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKS
LLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQ
SLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVA
DPWGGSYMMESLTNDVYEAALKLIYEVEEMGGMAKAVAE
GIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDSV
EVLAIDNTSVRKKQIEKLKKIKSSRDQALAEQCLSALTQ
CAASGDGNILALAVDAARARCTVGEITDALKKVFGEHKA
NDRMVSGAYRQEFGESKEITSAIKRVNKFMEREGRRPRL
LVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPRE
VAQQAVDADVHAVGVSTLAAGHKTLVPELIKELTALGRP
DILVMCGGVIPPQDYEFLYEVGVSNVFGPGTRIPRAAVQ
VLDDIEKCLAEKQQSV
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Tris-based buffer, 50% glycerol
storage stability :
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C,-80°C. The shelf life of lyophilized form is 12 months at -20°C,-80°C.Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
image1 heading :
SDS-PAGE
other info2 :
Tag Info: N-terminal 6xHis-tagged
products description :
Involved in the degradation of several amino acids, odd-chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle.
ncbi gi num :
148540106
ncbi acc num :
NP_032676.2
ncbi gb acc num :
NM_008650.3
uniprot acc num :
P16332
ncbi mol weight :
83.2kDa
ncbi pathways :
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (574763); Glyoxylate And Dicarboxylate Metabolism Pathway (83200); Glyoxylate And Dicarboxylate Metabolism Pathway (383); Metabolism Pathway (574739); Metabolism Of Lipids And Lipoproteins Pathway (574754); Mitochondrial Fatty Acid Beta-Oxidation Pathway (574768); Propanoate Metabolism Pathway (83202); Propanoate Metabolism Pathway (387); Propionyl-CoA Catabolism Pathway (574778); Valine, Leucine And Isoleucine Degradation Pathway (83152)
uniprot summary :
MUT: Involved in the degradation of several amino acids, odd- chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species. Defects in MUT are the cause of methylmalonic aciduria type mut (MMAM). MMAM is an often fatal disorder of organic acid metabolism. Common clinical features include lethargy, vomiting, failure to thrive, hypotonia, neurological deficit and early death. Two forms of the disease are distinguished by the presence (mut-) or absence (mut0) of residual enzyme activity. Mut0 patients have more severe neurological manifestations of the disease than do MUT- patients. MMAM is unresponsive to vitamin B12 therapy. Belongs to the methylmalonyl-CoA mutase family. Protein type: Amino Acid Metabolism - valine, leucine and isoleucine degradation; Carbohydrate Metabolism - propanoate; EC 5.4.99.2; Isomerase; Mitochondrial. Chromosomal Location of Human Ortholog: 17 B2 17 19.55 cM. Cellular Component: mitochondrion. Molecular Function: methylmalonyl-CoA mutase activity. Biological Process: homocysteine metabolic process; post-embryonic development
size1 :
0.01 mg
price1 :
265 USD
size2 :
0.05 mg
price2 :
350
size3 :
0.1 mg
price3 :
560
size4 :
0.2 mg
price4 :
880
size5 :
0.5 mg
price5 :
1145
size6 :
1 mg
price6 :
1795
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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