protein

Recombinant Human Dermcidin

MBS9422261

0.01 mg

200 USD

Recombinant Protein

Recombinant Human Dermcidin

[Dermcidin]

[Preproteolysin]

[dermcidin isoform 2 preproprotein; Dermcidin; dermcidin; dermcidin; Preproteolysin]

[DCD]

[DCD; DCD; PIF; AIDD; DSEP; HCAP; DCD-1; AIDD; DSEP]

Yeast

Human

[Full Length, 20-110aa]

YDPEAASAPGSGNPCHEASAAQKENAGEDPGLARQAPKP
RKQRSSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKG
AVHDVKDVLDSVL

Greater than 90% as determined by SDS-PAGE.

Tris-based buffer 50% glycerol

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C,-80°C. The shelf life of lyophilized form is 12 months at -20°C,-80°C. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Calculated MW: 11.3 kDa. Immunogen Description: Expression Region:20-110aaSequence Info:Full Length

Tag Info: N-terminal 6xHis-tagged

Recombinant protein. DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E Coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resble the conditions in sweat. Also exhibits proteolytic activity.Survival-promoting peptide promotes survival of neurons and displays phosphatase activity. It may bind IgG.

665505971

NP_001287783.1

NP_001287783.1

P81605

Antimicrobial Peptides Pathway (1457777); Immune System Pathway (1269170); Innate Immune System Pathway (1269203)

This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]

DCD: DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.4.-.-; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 12q13.2. Cellular Component: extracellular matrix; extracellular region. Molecular Function: protein binding; RNA binding. Biological Process: antimicrobial humoral response

0.01 mg

200 USD

0.05 mg

250

0.1 mg

380

0.2 mg

590

0.5 mg

950

1 mg

1475