catalog number :
MBS9421470
products type :
Recombinant Protein
products full name :
Recombinant human Angiopoietin-related protein 2
products short name :
[Angiopoietin-related protein 2]
products name syn :
[Angiopoietin-like protein 2]
other names :
[angiopoietin-related protein 2; Angiopoietin-related protein 2; angiopoietin-related protein 2; angiopoietin like 2; Angiopoietin-like protein 2]
products gene name :
[ANGL2]
other gene names :
[ANGPTL2; ANGPTL2; ARP2; HARP; ARP2]
sequence positions :
[Full Length, 23-493aa]
sequence :
QEDGFEGTEEGSPREFIYLNRYKRAGESQDKCTYTFIVP
QQRVTGAICVNSKEPEVLLENRVHKQELELLNNELLKQK
RQIETLQQLVEVDGGIVSEVKLLRKESRNMNSRVTQLYM
QLLHEIIRKRDNALELSQLENRILNQTADMLQLASKYKD
LEHKYQHLATLAHNQSEIIAQLEEHCQRVPSARPVPQPP
PAAPPRVYQPPTYNRIINQISTNEIQSDQNLKVLPPPLP
TMPTLTSLPSSTDKPSGPWRDCLQALEDGHDTSSIYLVK
PENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWE
TYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWS
GRKVFAEYASFRLEPESEYYKLRLGRYHGNAGDSFTWHN
GKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGV
WYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRPNPN
TFH
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Tris-based buffer50% glycerol
storage stability :
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stabilityof the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C,-80°C. The shelf life of lyophilized form is 12 months at -20°C,-80°C. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
other info1 :
Immunogen Description: Expression Region:23-493aaSequence Info:Full Length. Calculated MW: 70.8 kDa. Tag Info: N-terminal 6xHis-SUMO-tagged
products description :
Induces sprouting in endothelial cells through an autocrine and paracrine action.
ncbi acc num :
NP_036230.1
ncbi gb acc num :
NM_012098.2
ncbi summary :
Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. [provided by RefSeq, Jul 2008]
uniprot summary :
ANGPTL2: Induces sprouting in endothelial cells through an autocrine and paracrine action. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 9q33.3. Cellular Component: extracellular space. Molecular Function: receptor binding. Biological Process: multicellular organismal development