catalog number :
MBS9419181
products full name :
ATP5O Antibody
products short name :
[ATP5O]
products name syn :
[ATP5O; ATPO; OSCP]
other names :
[ATP synthase subunit O, mitochondrial; ATP synthase subunit O, mitochondrial; ATP synthase subunit O, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit; Oligomycin sensitivity conferral protein; OSCP]
products gene name :
[ATP5O]
other gene names :
[ATP5O; ATP5O; ATPO; OSCP; HMC08D05; ATPO; OSCP]
uniprot entry name :
ATPO_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
ATP5O Antibody detects endogenous levels of total ATP5O
purity :
Immunogen affinity purified.
form :
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20°C
tested application :
Western Blot (WB)
app notes :
Western Blot: 1:1000-3000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthesized peptide derived from human ATP5O. Immunogen Type: Peptide
other info2 :
Calculated MW: 23kDa
products categories :
Total protein Ab
ncbi acc num :
NP_001688.1
ncbi gb acc num :
NM_001697.2
ncbi mol weight :
23,277 Da
ncbi pathways :
Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Electron Transport Chain Pathway (198860); F-type ATPase, Eukaryotes Pathway (522535); F-type ATPase, Eukaryotes Pathway (890450); Formation Of ATP By Chemiosmotic Coupling Pathway (1270129); Huntington's Disease Pathway (83100); Huntington's Disease Pathway (512); Metabolic Pathways (132956); Metabolism Pathway (1269956)
ncbi summary :
The protein encoded by this gene is a component of the F-type ATPase found in the mitochondrial matrix. F-type ATPases are composed of a catalytic core and a membrane proton channel. The encoded protein appears to be part of the connector linking these two components and may be involved in transmission of conformational changes or proton conductance. [provided by RefSeq, Jul 2008]
uniprot summary :
ATP5O: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Belongs to the ATPase delta chain family. Protein type: EC 3.6.3.14; Energy Metabolism - oxidative phosphorylation; Hydrolase; Mitochondrial. Chromosomal Location of Human Ortholog: 21q22.11. Cellular Component: extracellular matrix; mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrion; nucleus; plasma membrane. Molecular Function: ATPase activity; drug binding; protein binding; transmembrane transporter activity. Biological Process: ATP biosynthetic process; mitochondrial ATP synthesis coupled proton transport