catalog number :
MBS9419170
products full name :
SLC7A10 Antibody
products short name :
[SLC7A10]
products name syn :
[SLC7A10; ASC1; ASC-1; HASC-1]
other names :
[asc-type amino acid transporter 1; Asc-type amino acid transporter 1; asc-type amino acid transporter 1; solute carrier family 7 member 10; Solute carrier family 7 member 10]
products gene name :
[SLC7A10]
other gene names :
[SLC7A10; SLC7A10; ASC1; asc-1; HASC-1; ASC1; Asc-1]
uniprot entry name :
AAA1_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
SLC7A10 Antibody detects endogenous levels of total SLC7A10
purity :
Immunogen Affinity purified
form :
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20°C
tested application :
Western Blot (WB)
app notes :
Western Blot: 1:1000-3000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthesized peptide derived from human SLC7A10. Immunogen Type: Peptide. Calculated MW: 57 kDa
products categories :
Total protein Ab
ncbi acc num :
NP_062823.1
ncbi gb acc num :
NM_019849.2
ncbi pathways :
Amino Acid Transport Across The Plasma Membrane Pathway (1269916); Basigin Interactions Pathway (1269376); Cell Surface Interactions At The Vascular Wall Pathway (1269373); Differentiation Of White And Brown Adipocyte Pathway (1458280); Hemostasis Pathway (1269340); SLC-mediated Transmembrane Transport Pathway (1269907); Transmembrane Transport Of Small Molecules Pathway (1269903); Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway (1269908)
ncbi summary :
SLC7A10, in association with 4F2HC (SLC3A2; MIM 158070), mediates high-affinity transport of D-serine and several other neutral amino acids (Nakauchi et al., 2000 [PubMed 10863037]).[supplied by OMIM, Mar 2008]
uniprot summary :
SLC7A10: Sodium-independent, high affinity transport of small neutral D- and L-amino acids. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family. Chromosomal Location of Human Ortholog: 19q13.1. Cellular Component: membrane; plasma membrane. Molecular Function: antiporter activity; L-serine transmembrane transporter activity; neutral amino acid transmembrane transporter activity. Biological Process: amino acid transport; D-alanine transport; D-serine transport; leukocyte migration; neutral amino acid transport