product summary
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company name :
MyBioSource
product type :
antibody
product name :
Defensin alpha4 Antibody
catalog :
MBS9418724
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
more info or order :
image
image 1 :
Western blot analysis Defensin alpha4 using HuvEc whole cell lysates
product information
catalog number :
MBS9418724
products type :
Antibody
products full name :
Defensin alpha4 Antibody
products short name :
[Defensin alpha4]
products name syn :
[DEFA4; DEF4; Corticostatin; HNP-4; HP-4; HP4; Defensin; alpha 4; Neutrophil defensin 4]
other names :
[neutrophil defensin 4 preproprotein; Neutrophil defensin 4; neutrophil defensin 4; defensin alpha 4; Defensin, alpha 4; HNP-4; HP-4]
other gene names :
[DEFA4; DEFA4; HP4; DEF4; HP-4; HNP-4; DEF4; HP-4]
uniprot entry name :
DEF4_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
sequence length :
97
specificity :
Defensin alpha4 Antibody detects endogenous levels of total Defensin alpha4
purity :
Immunogen affinity purified
form :
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1.0mg/mL
storage stability :
Store at -20 degree C
tested application :
Western Blot (WB)
app notes :
Western Blot: 1:1000-3000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen Description: A synthesized peptide derived from human Defensin alpha4. Immunogen Type: Peptide
other info2 :
Calculated MW: 10kDa. Target Name: Defensin alpha 4
products categories :
Total protein Ab
ncbi gi num :
4503303
ncbi acc num :
NP_001916.1
ncbi gb acc num :
NM_001925.2
uniprot acc num :
P12838
ncbi pathways :
Alpha-defensins Pathway (1269266); Antimicrobial Peptides Pathway (1457777); Defensins Pathway (1269265); Immune System Pathway (1269170); Innate Immune System Pathway (1269203); Neutrophil Degranulation Pathway (1457780)
ncbi summary :
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Oct 2014]
uniprot summary :
DEFA4: Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Protects blood cells against infection with HIV-1 (in vitro). Inhibits corticotropin (ACTH)-stimulated corticosterone production. Belongs to the alpha-defensin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 8p23. Cellular Component: azurophil granule; extracellular region; Golgi lumen. Biological Process: antibacterial humoral response; antimicrobial humoral response; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; innate immune response
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
255
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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