catalog number :
MBS9418316
products full name :
GPR31 Antibody
products short name :
[GPR31]
products name syn :
[12-(S)-HETE acid receptor antibody, 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (HETE) receptor antibody, 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor antibody, 12-(S)-HYDROXYEICOSATETRAENOIC ACID RECEPTOR antibody, 12-HETER antibody, bA517H2.2]
other names :
[12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor; 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor; 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor; G protein-coupled receptor 31; G-protein coupled receptor 31]
products gene name :
[GPR31]
other gene names :
[GPR31; GPR31; HETER; HETER1; 12-HETER; 12-(S)-HETE receptor; 12-HETER]
uniprot entry name :
GPR31_HUMAN
specificity :
GPR31antibody detects endogenous levels of total GPR31
purity :
Immunogen affinity purified
form :
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20°C
tested application :
Western Blot (WB)
app notes :
Western Blot: 1:500-1:2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthesized peptide derived from human GPR31. Immunogen Type: Peptide. Target Name: GPR31
products categories :
Total protein Ab
ncbi acc num :
NP_005290.2
ncbi gb acc num :
NM_005299.2
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); Free Fatty Acid Receptors Pathway (1269569); GPCR Ligand Binding Pathway (1269544); GPCRs, Class A Rhodopsin-like Pathway (198886); Signal Transduction Pathway (1269379); Signaling By GPCR Pathway (1269543)
uniprot summary :
GPR31: High-affinity receptor for 12-(S)-hydroxy-5,8,10,14- eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Receptor, GPCR. Chromosomal Location of Human Ortholog: 6q27. Cellular Component: integral to plasma membrane; plasma membrane