product summary
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company name :
MyBioSource
product type :
antibody
product name :
K2C1 Antibody
catalog :
MBS9418228
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
more info or order :
image
image 1 :
Western blot analysis of K2C1 expression in HEK293 cells,The lane on the left is treated with the antigen-specific peptide.
product information
catalog number :
MBS9418228
products type :
Antibody
products full name :
K2C1 Antibody
products short name :
[K2C1]
products name syn :
[KRT1]
other names :
[keratin, type II cytoskeletal 1; Keratin, type II cytoskeletal 1; keratin, type II cytoskeletal 1; keratin 1; 67 kDa cytokeratin; Cytokeratin-1; CK-1; Hair alpha protein; Keratin-1; K1; Type-II keratin Kb1]
products gene name :
[K2C1]
other gene names :
[KRT1; KRT1; K1; CK1; EHK; EHK1; EPPK; KRT1A; NEPPK; KRTA; CK-1; K1]
uniprot entry name :
K2C1_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
644
specificity :
K2C1antibody detects endogenous levels of total K2C1
purity :
Immunogen affinity purified
form :
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1.0mg/mL
storage stability :
Store at -20 degree C
tested application :
Western Blot (WB)
app notes :
Western Blot: 1:500-1:2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthesized peptide derived from human K2C1. Immunogen Type: Peptide
products categories :
Total protein Ab
ncbi gi num :
119395750
ncbi acc num :
NP_006112.3
ncbi gb acc num :
NM_006121.3
uniprot acc num :
P04264
ncbi mol weight :
66 kDa
ncbi pathways :
Corticotropin-releasing Hormone Signaling Pathway (920957); Developmental Biology Pathway (1270302); Immune System Pathway (1269170); Innate Immune System Pathway (1269203); Keratinization Pathway (1457790); Neutrophil Degranulation Pathway (1457780); Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway (169352)
ncbi summary :
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
uniprot summary :
K1: a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Generally associates with K10. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 12q13.13. Cellular Component: cytoskeleton; extracellular matrix; extracellular space; membrane; nucleus. Molecular Function: carbohydrate binding; protein binding. Biological Process: complement activation, lectin pathway; retinal homeostasis. Disease: Epidermolytic Hyperkeratosis; Ichthyosis Hystrix, Curth-macklin Type; Ichthyosis, Cyclic, With Epidermolytic Hyperkeratosis; Keratosis Palmoplantaris Striata Iii; Palmoplantar Keratoderma, Epidermolytic; Palmoplantar Keratoderma, Nonepidermolytic
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
255
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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