catalog number :
MBS9417260
products full name :
B4GAT1 Antibody
products short name :
[B4GAT1]
products name syn :
[iGAT; iGNT; B3GNT1; B3GNT6; B3GN-T1; MDDGA13; BETA3GNTI]
other names :
[beta-1,4-glucuronyltransferase 1; Beta-1,4-glucuronyltransferase 1; beta-1,4-glucuronyltransferase 1; beta-1,4-glucuronyltransferase 1; I-beta-1,3-N-acetylglucosaminyltransferase; iGnT; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; Poly-N-acetyllactosamine extension enzyme; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1]
products gene name :
[B4GAT1]
other gene names :
[B4GAT1; B4GAT1; iGAT; iGNT; B3GNT1; B3GNT6; B3GN-T1; MDDGA13; BETA3GNTI; iGnT]
uniprot entry name :
B4GA1_HUMAN
reactivity :
Human, Mouse
specificity :
The antibody detects endogenous levels of total B4GAT1 protein.
purity :
Antigen affinity purification
form :
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
storage stability :
Store at -20°C
tested application :
Western Blot (WB)
app notes :
Western Blot: 1:500-2000
image1 heading :
SDS-Page
other info1 :
Immunogen: Synthetic peptide of human B4GAT1. Immunogen Type: Peptide
other info2 :
Calculated MW: 47 kD
products categories :
Total protein Ab
products description :
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It is essential for the synthesis of poly-N-acetyllactosamine, a determinant for the blood group i antigen.
ncbi acc num :
NP_006867.1
ncbi gb acc num :
NM_006876.2
ncbi pathways :
Glycosaminoglycan Metabolism Pathway (1269972); Keratan Sulfate Biosynthesis Pathway (1269978); Keratan Sulfate/keratin Metabolism Pathway (1269977); Mannose Type O-glycan Biosynthesis Pathway (1469011); Mannose Type O-glycan Biosynthesis Pathway (1468887); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Carbohydrates Pathway (1269957); Metabolism Of Proteins Pathway (1268677); O-linked Glycosylation Pathway (1268734)
ncbi summary :
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It is essential for the synthesis of poly-N-acetyllactosamine, a determinant for the blood group i antigen. [provided by RefSeq, Jul 2008]
uniprot summary :
B4GAT1: Can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans. Protein type: EC 2.4.1.149; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Glycan Metabolism - keratan sulfate biosynthesis; Membrane protein, integral; Transferase. Chromosomal Location of Human Ortholog: 11q13.2. Cellular Component: Golgi apparatus; Golgi membrane. Molecular Function: glucuronosyltransferase activity; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity. Biological Process: keratan sulfate biosynthetic process; poly-N-acetyllactosamine biosynthetic process; protein amino acid O-linked mannosylation. Disease: Muscular Dystrophy-dystroglycanopathy (congenital With Brain And Eye Anomalies), Type A, 13