product summary
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company name :
MyBioSource
product type :
antibody
product name :
SDC2 Antibody
catalog :
MBS9417111
quantity :
0.1 mL
price :
255 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
immunohistochemistry
more info or order :
image
image 1 :
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using SDC2 Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
product information
catalog number :
MBS9417111
products type :
Antibody
products full name :
SDC2 Antibody
products short name :
[SDC2]
products name syn :
[HSPG; CD362; HSPG1; SYND2]
other names :
[syndecan-2; Syndecan-2; syndecan-2; syndecan 2; Fibroglycan; Heparan sulfate proteoglycan core protein; HSPG; CD_antigen: CD362]
products gene name :
[SDC2]
other gene names :
[SDC2; SDC2; HSPG; CD362; HSPG1; SYND2; HSPG1; SYND2; HSPG]
uniprot entry name :
SDC2_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
201
specificity :
The antibody detects endogenous levels of total SDC2 protein.
purity :
Antigen affinity purification
form :
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
concentration :
0.5mg/ml
storage stability :
Store at -20°C
tested application :
Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: 1: 20-100
image1 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Synthetic peptide of human SDC2. Immunogen Type: Peptide. Target: SDC2
products categories :
Total protein Ab
products description :
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.
ncbi gi num :
40548378
ncbi acc num :
NP_002989.2
ncbi gb acc num :
NM_002998.3
uniprot acc num :
P34741
ncbi pathways :
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway (1269981); Axon Guidance Pathway (1270303); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Surface Interactions At The Vascular Wall Pathway (1269373); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (1269984); Defective B3GALT6 Causes EDSP2 And SEMDJL1 Pathway (1309217); Defective B3GAT3 Causes JDSSDHD Pathway (1269015); Defective B4GALT7 Causes EDS, Progeroid Type Pathway (1269014); Defective EXT1 Causes Exostoses 1, TRPS2 And CHDS Pathway (1269021)
ncbi summary :
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008]
uniprot summary :
syndecan-2: a heparan sulfate proteoglycan type I membrane protein that belongs to the syndecan proteoglycan family. Preferentially expressed in cells of mesenchymal origin. Is tyrosine phosphorylated and forms a complex with EphB2 in mouse brain. Plays a role in mediating adhesion and proliferation of colon carcinoma cells. Protein type: Cell adhesion; Cell surface; Membrane protein, integral; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 8q22-q23. Cellular Component: cell surface; Golgi lumen; lysosomal lumen; plasma membrane. Molecular Function: PDZ domain binding; protein binding. Biological Process: cell migration; dendrite morphogenesis; ephrin receptor signaling pathway; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; glycosaminoglycan metabolic process; regulation of dendrite morphogenesis; retinoid metabolic process
size1 :
0.1 mL
price1 :
255 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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