catalog number :
MBS9415650
products full name :
STX12 Antibody
products short name :
[STX12]
products name syn :
[STX13; STX14]
other names :
[syntaxin-12; Syntaxin-12; syntaxin-12; syntaxin 12]
products gene name :
[STX12]
other gene names :
[STX12; STX12; STX13; STX14]
uniprot entry name :
STX12_HUMAN
reactivity :
Human, Mouse
specificity :
The antibody detects endogenous levels of total STX12 protein.
purity :
Antigen Affinity Purification
form :
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
concentration :
2.1 mg/ml
storage stability :
Store at -20°C
tested application :
Western Blot (WB)
app notes :
Western Blot: 1:1000-1:5000. Immunohistochemistry: 1:30-1:150
image1 heading :
Western Blot (WB)
other info1 :
Immunogen Type: Protein
other info2 :
Immunogen Description: Full length fusion protein of human STX12. Calculated MW: 32kd
products categories :
Total protein Ab
products description :
Syntaxin 12, also known as STX12, STX13 or STX14, is a 276 amino acid single-pass membrane protein that contains one t-SNARE coiled-coil homology domain and belongs to the Syntaxin family. Syntaxin 12 regulates protein transport between late endosomes and the trans-Golgi network and interacts with ABC1 (ATP-binding cassette transporter A1), a protein that facilitates cellular release of choline-phospholipids and cholesterol to apoA-I (apolipoprotein A-I).
ncbi acc num :
NP_803173.1
ncbi gb acc num :
NM_177424.2
ncbi pathways :
Phagosome Pathway (153910); Phagosome Pathway (153859)
uniprot summary :
STX12: SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro). Belongs to the syntaxin family. Protein type: Membrane protein, integral; Vesicle. Chromosomal Location of Human Ortholog: 1p35.3. Cellular Component: endomembrane system; integral to membrane; lipid raft; phagocytic vesicle; SNARE complex; vesicle. Molecular Function: protein binding; SNAP receptor activity; SNARE binding. Biological Process: autophagic vacuole formation; cholesterol efflux; intracellular protein transport; protein stabilization; vesicle docking; vesicle fusion