product summary
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company name :
MyBioSource
product type :
antibody
product name :
Metalloproteinase inhibitor 3 Polyclonal Antibody
catalog :
MBS9415370
quantity :
0.1 mL
price :
320 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
MyBioSource MBS9415370 image 1
All lanes:Metalloproteinase inhibitor 3 antibody at 2ug/ml. Lane1: EC109 whole cell lysateLane 2:293T whole cell lysate . secondary Goat polyclonal to rabbit at 1/10000. dilution predicted band size : 24kDa . observed band size :24kDa
product information
catalog number :
MBS9415370
products type :
Antibody
products full name :
Metalloproteinase inhibitor 3 Polyclonal Antibody
products short name :
[Metalloproteinase inhibitor 3]
products name syn :
[Protein MIG-5; Tissue inhibitor of metalloproteinases 3; TIMP3]
other names :
[metalloproteinase inhibitor 3; Metalloproteinase inhibitor 3; metalloproteinase inhibitor 3; TIMP metallopeptidase inhibitor 3; Protein MIG-5; Tissue inhibitor of metalloproteinases 3; TIMP-3]
other gene names :
[TIMP3; TIMP3; SFD; K222; K222TA2; HSMRK222; TIMP-3]
uniprot entry name :
TIMP3_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
sequence length :
211
specificity :
The antibody detects endogenous level of total Metalloproteinase inhibitor 3 polyclonal antibody.
purity :
Caprylic Acid Ammonium Sulfate Precipitation purified
form :
Preservative: 0.03% Proclin 300 . Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
concentration :
1.0 mg/ml
storage stability :
Store at -20°C
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western Blot: 1:500 - 1:1000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant Human Metalloproteinase inhibitor 3 protein. Calculated MW: 24 kD
other info2 :
Immunogen Type: Protein
products categories :
Total protein Ab
products description :
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
ncbi gi num :
4507513
ncbi acc num :
NP_000353.1
ncbi gb acc num :
NM_000362.4
uniprot acc num :
P35625
ncbi pathways :
Angiogenesis Pathway (198772); Endochondral Ossification Pathway (198812); Matrix Metalloproteinases Pathway (198900); MicroRNAs In Cancer Pathway (852705); MicroRNAs In Cancer Pathway (852928); Oncostatin M Signaling Pathway (711361); Proteoglycans In Cancer Pathway (782000); Proteoglycans In Cancer Pathway (782054)
uniprot summary :
TIMP3: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15. Interacts with EFEMP1. Belongs to the protease inhibitor I35 (TIMP) family. Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 22q12.3. Cellular Component: extracellular matrix; extracellular region; extracellular space; nucleus; proteinaceous extracellular matrix. Molecular Function: metalloendopeptidase inhibitor activity; protease binding; protein binding. Biological Process: negative regulation of membrane protein ectodomain proteolysis; platelet degranulation; response to organic substance. Disease: Fundus Dystrophy, Pseudoinflammatory, Of Sorsby
size1 :
0.1 mL
price1 :
320 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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