product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
CD63 Antibody
catalog :
MBS9414654
quantity :
0.1 mL
price :
255 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Gel: 12%SDS-PAGE. Lysates (from left to right): NIH/3T3, K562 and 293T cell. Amount of lysate: 40ug per lane. Primary antibody: 1/200 dilution. Secondary antibody dilution: 1/8000. Exposure time: 20 seconds
image 2 :
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/25.
product information
catalog number :
MBS9414654
products type :
Antibody
products full name :
CD63 Antibody
products short name :
[CD63]
products name syn :
[MLA1; ME491; LAMP-3; OMA81H; TSPAN30]
other names :
[CD63 antigen isoform A; CD63 antigen; CD63 antigen; CD63 molecule; Granulophysin; Lysosomal-associated membrane protein 3; LAMP-3; Melanoma-associated antigen ME491; OMA81H; Ocular melanoma-associated antigen; Tetraspanin-30; Tspan-30; CD_antigen: CD63]
products gene name :
[CD63]
other gene names :
[CD63; CD63; MLA1; ME491; LAMP-3; OMA81H; TSPAN30; MLA1; TSPAN30; LAMP-3; Tspan-30]
uniprot entry name :
CD63_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
238
specificity :
The antibody detects endogenous levels of total CD63 protein.
purity :
Antigen affinity purification.
form :
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
concentration :
1.5 mg/ml
storage stability :
Store at -20°C
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western blotting: 1:500-1:2000. Immunohistochemistry: 1:25-1:100
image1 heading :
Testing Data
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen Type: Peptide. Immunogen Description: Synthetic peptide of human CD63 molecule. SDS-PAGE MW: 26 KD
other info2 :
Target Name: CD63
products categories :
Total protein Ab
products description :
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
ncbi gi num :
383872447
ncbi acc num :
NP_001244318.1
ncbi gb acc num :
NM_001257389.1
uniprot acc num :
P08962
ncbi pathways :
Hemostasis Pathway (1269340); Lysosome Pathway (99052); Lysosome Pathway (96865); Platelet Activation, Signaling And Aggregation Pathway (1269350); Platelet Degranulation Pathway (1269367); Proteoglycans In Cancer Pathway (782000); Proteoglycans In Cancer Pathway (782054); Response To Elevated Platelet Cytosolic Ca2+ Pathway (1269365)
ncbi summary :
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
uniprot summary :
CD63: This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation. Belongs to the tetraspanin (TM4SF) family. Protein type: Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 12q12-q13. Cellular Component: cell surface; integral to plasma membrane; late endosome membrane; lysosomal membrane; melanosome; plasma membrane; endosome membrane; platelet dense granule membrane; intrinsic to plasma membrane. Molecular Function: protein binding. Biological Process: platelet activation; protein transport; cell migration; pigment granule maturation; platelet degranulation; cell-matrix adhesion; positive regulation of receptor internalization; blood coagulation
size1 :
0.1 mL
price1 :
255 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!
related products
browse more products
questions and comments