catalog number :
MBS9414054
products full name :
TRIM14 Antibody
products short name :
[TRIM14]
other names :
[tripartite motif-containing protein 14; Tripartite motif-containing protein 14; tripartite motif-containing protein 14; tripartite motif containing 14]
products gene name :
[TRIM14]
other gene names :
[TRIM14; TRIM14; KIAA0129]
uniprot entry name :
TRI14_HUMAN
specificity :
The antibody detects endogenous levels of total TRIM14 protein.
purity :
Antigen affinity purification.
form :
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
concentration :
2.2 mg/ml
storage stability :
Store at -20 degree C
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western blotting: 1:500-1:2000. Immunohistochemistry: 1:30-1:150
image1 heading :
Testing Data
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen Type: Protein. Immunogen Description: Fusion protein corresponding to residues near the C terminal of human tripartite motif containing 14. SDS-PAGE MW: 50 kD
other info2 :
Target Name: TRIM14
products categories :
Total protein Ab
products description :
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies and its function has not been determined. Alternative splicing results in multiple transcript variants.
ncbi acc num :
NP_055603.2
ncbi gb acc num :
NM_014788.3
ncbi pathways :
Cytokine Signaling In Immune System Pathway (1269310); Immune System Pathway (1269170); Interferon Signaling Pathway (1269311); Interferon Gamma Signaling Pathway (1269314)
ncbi summary :
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies and its function has not been determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
uniprot summary :
TRIM14: Inhibits the transcriptional activity of SPI1 in a dose- dependent manner. Belongs to the TRIM/RBCC family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription regulation. Chromosomal Location of Human Ortholog: 9q22.33. Cellular Component: cytoplasm; intracellular. Molecular Function: zinc ion binding. Biological Process: negative regulation of viral transcription; innate immune response; positive regulation of transcription factor activity; activation of NF-kappaB transcription factor