product summary
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company name :
MyBioSource
product type :
antibody
product name :
PGE synthase Polyclonal Antibody
catalog :
MBS9413039
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
more info or order :
image
image 1 :
Western Blot analysis of A549 cells using PGE synthase Polyclonal Antibody
product information
catalog number :
MBS9413039
products type :
Antibody
products full name :
PGE synthase Polyclonal Antibody
products short name :
[PGE synthase]
products name syn :
[PTGES; MGST1L1; MPGES1; PGES; PIG12; Prostaglandin E synthase; Microsomal glutathione S-transferase 1-like 1; MGST1-L1; Microsomal prostaglandin E synthase 1; MPGES-1; p53-induced gene 12 protein]
other names :
[prostaglandin E synthase; Prostaglandin E synthase; prostaglandin E synthase; prostaglandin E synthase; Microsomal glutathione S-transferase 1-like 1; MGST1-L1; Microsomal prostaglandin E synthase 1; MPGES-1; p53-induced gene 12 protein]
products gene name :
[PGE]
other gene names :
[PTGES; PTGES; PGES; MPGES; PIG12; PP102; PP1294; MGST-IV; MGST1L1; TP53I12; mPGES-1; MGST1-L1; MGST1L1; MPGES1; PGES; PIG12; MGST1-L1; MPGES-1]
uniprot entry name :
PTGES_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
152
specificity :
PGE synthase Polyclonal Antibody detects endogenous levels of PGE synthase protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
concentration :
1 mg/ml
storage stability :
Store at -20 degree C/1 year
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
Western Blot: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
image1 heading :
Western Blot (WB)
other info1 :
Immunogen Type: peptide. Immunogen Description: Synthesized peptide derived from the Internal region of human PGE synthase.
other info2 :
Target Name: PGE synthase
products categories :
Total protein Ab
ncbi gi num :
4758910
ncbi acc num :
NP_004869.1
ncbi gb acc num :
NM_004878.4
uniprot acc num :
O14684
ncbi mol weight :
17kd
ncbi pathways :
Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (1270087); Arachidonic Acid Metabolism Pathway (366); Eicosanoid Synthesis Pathway (198888); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001); Synthesis Of Prostaglandins (PG) And Thromboxanes (TX) Pathway (1270088)
ncbi summary :
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008]
uniprot summary :
PTGES: Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Belongs to the MAPEG family. Protein type: EC 5.3.99.3; Nuclear envelope; Isomerase; Membrane protein, multi-pass; Membrane protein, integral; Lipid Metabolism - arachidonic acid. Chromosomal Location of Human Ortholog: 9q34.3. Cellular Component: endoplasmic reticulum membrane; membrane; nuclear envelope lumen; perinuclear region of cytoplasm; integral to membrane. Molecular Function: glutathione binding; prostaglandin-E synthase activity. Biological Process: chronic inflammatory response; response to retinoic acid; cyclooxygenase pathway; response to lipopolysaccharide; prostaglandin biosynthetic process; signal transduction; response to organic cyclic substance; prostaglandin metabolic process; negative regulation of cell proliferation; response to cytokine stimulus; arachidonic acid metabolic process; response to calcium ion; acute inflammatory response
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
255
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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