catalog number :
MBS9412829
products full name :
GPR39 Antibody
products short name :
[GPR39]
products name syn :
[G protein-coupled receptor 39; G-protein coupled receptor 39; GPR39; MGC149541]
other names :
[G-protein coupled receptor 39; G-protein coupled receptor 39; G-protein coupled receptor 39; G protein-coupled receptor 39]
products gene name :
[GPR39]
other gene names :
[GPR39; GPR39]
uniprot entry name :
GPR39_HUMAN
specificity :
The antibody detects endogenous levels of total GPR39 protein.
purity :
Antigen affinity purification.
form :
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
concentration :
2.6 mg/ml
storage stability :
Store at -20°C.
tested application :
Western Blot (WB)
app notes :
Western blotting: 1:200-1:1000
image1 heading :
Testing Data
other info1 :
Immunogen Type: Peptide. Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human G protein-coupled receptor 39
other info2 :
Target Name: GPR39
products categories :
Total protein Ab
products description :
G-protein coupled receptor 39 is a protein that in humans is encoded by the GPR39 gene. The predicted 453-amino acid GPR39 protein contains the 7 transmembrane domains characteristic of GPCRs. By sequence comparison with other GPCRs, the protein sequence of GPR39 is 27% and 32% identical to that of GSHR and neurotensin receptor-1, respectively. Northern blot analysis revealed that GPR39 is expressed widely as a 1.8- to 2-kb mRNA. A 3-kb transcript is present on Northern blots of some tissues, either in addition to the smaller mRNA or as the only hybridizing band.
ncbi gb acc num :
NM_001508.2
ncbi mol weight :
SDS-PAGE MW: 51kd
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); GPCR Ligand Binding Pathway (1269544); GPCRs, Class A Rhodopsin-like Pathway (198886); Signal Transduction Pathway (1269379); Signaling By GPCR Pathway (1269543)
uniprot summary :
GPR39: Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral. Chromosomal Location of Human Ortholog: 2q21-q22. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: G-protein coupled receptor activity; metal ion binding. Biological Process: G-protein coupled receptor protein signaling pathway