product summary
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company name :
MyBioSource
product type :
antibody
product name :
TRAF7 Antibody
catalog :
MBS9412543
quantity :
0.1 mL
price :
255 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Gel: 8%SDS-PAGE Lysate: 40ug Jurkat cell Primary antibody: 1/300 dilution Secondary antibody dilution: 1/8000 Exposure time: 2 minutes
image 2 :
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using at dilution 1/20.
product information
catalog number :
MBS9412543
products type :
Antibody
products full name :
TRAF7 Antibody
products short name :
[TRAF7]
products name syn :
[RFWD1; RNF119]
other names :
[E3 ubiquitin-protein ligase TRAF7; E3 ubiquitin-protein ligase TRAF7; E3 ubiquitin-protein ligase TRAF7; TNF receptor-associated factor 7, E3 ubiquitin protein ligase; RING finger and WD repeat-containing protein 1; RING finger protein 119; TNF receptor-associated factor 7]
products gene name :
[TRAF7]
other gene names :
[TRAF7; TRAF7; RFWD1; RNF119; RFWD1; RNF119]
uniprot entry name :
TRAF7_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
sequence length :
670
specificity :
The antibody detects endogenous levels of total TRAF7 protein.
purity :
Antigen affinity purification.
form :
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
concentration :
0.7 mg/ml
storage stability :
Store at -20°C
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western blotting: 1:200-1:1000. Immunohistochemistry: 1:15-1:50
image1 heading :
Testing Data
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen Type: Peptide. Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human TNF receptor-associated factor 7, E3 ubiquitin protein ligase
other info2 :
Target Name: TRAF7
products categories :
Total protein Ab
products description :
Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.
ncbi gi num :
45594312
ncbi acc num :
NP_115647.2
ncbi gb acc num :
NM_032271.2
uniprot acc num :
Q6Q0C0
ncbi pathways :
Adaptive Immune System Pathway (1269171); Antigen Processing: Ubiquitination Proteasome Degradation Pathway (1269193); Class I MHC Mediated Antigen Processing Presentation Pathway (1269192); Immune System Pathway (1269170)
ncbi summary :
Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.[supplied by OMIM, Apr 2004]
uniprot summary :
TRAF7: E3 ubiquitin ligase capable of auto-ubiquitination, following phosphorylation by MAP3K3. Potentiates MEKK3-mediated activation of the NF-kappa-B, JUN/AP1 and DDIT3 transcriptional regulators. Induces apoptosis when overexpressed. Belongs to the WD repeat TRAF7 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Ligase; EC 6.3.2.-; Ubiquitin ligase; EC 6.3.2.19; Ubiquitin conjugating system. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: intracellular membrane-bound organelle; perinuclear region of cytoplasm; cytoplasmic membrane-bound vesicle; plasma membrane; nucleus; cytosol; ubiquitin ligase complex. Molecular Function: protein binding; zinc ion binding; ubiquitin-protein ligase activity; ligase activity. Biological Process: positive regulation of protein sumoylation; regulation of protein localization; positive regulation of MAPKKK cascade; transcription, DNA-dependent; apoptosis; activation of MAPKKK activity; protein ubiquitination; negative regulation of transcription from RNA polymerase II promoter
size1 :
0.1 mL
price1 :
255 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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