catalog number :
MBS9411464
products full name :
gp120 Antibody
products short name :
[gp120]
products name syn :
[HIV-1 glycoprotein 120]
other names :
[envelope glycoprotein, partial; Envelope glycoprotein gp160]
products gene name :
[gp120]
uniprot entry name :
Q6BBS3_9HIV1
purity :
Affinity chromatography purified via peptide column
form :
Supplied in PBS containing 0.02% sodium azide.
storage stability :
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB)
image1 heading :
Western Blot (WB)
other info1 :
Immunogen Type: Peptide. Immunogen Description: Raised against 16 amino acid peptide representing the major HIV-1 consensus sequence near the N-terminal region of V1/V2 loop.
other info2 :
Target Name: gp120
products categories :
Total protein Ab
products description :
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.