catalog number :
MBS9409613
products full name :
GPA33 Antibody
products short name :
[GPA33]
products name syn :
[A33]
other names :
[cell surface A33 antigen; Cell surface A33 antigen; cell surface A33 antigen; glycoprotein A33 (transmembrane); Glycoprotein A33]
products gene name :
[GPA33]
other gene names :
[GPA33; GPA33; A33]
uniprot entry name :
GPA33_HUMAN
specificity :
The antibody detects endogenous levels of total GPA33 protein.
purity :
Antigen affinity purification.
form :
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
storage stability :
Store at -20°C
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western blotting: 1:500-1:2000. Immunohistochemistry: 1:50-1:200
image1 heading :
Testing Data
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen Type: Recombinant Protein. Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human glycoprotein A33 (transmembrane). SDS-PAGE MW: 36kD
other info2 :
Target Name: GPA33
products categories :
Total protein Ab
products description :
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
ncbi gb acc num :
NM_005814.2
ncbi summary :
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. [provided by RefSeq, Jul 2008]
uniprot summary :
GPA33: May play a role in cell-cell recognition and signaling. Protein type: Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 1q24.1. Cellular Component: integral to plasma membrane. Molecular Function: receptor activity