product summary
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company name :
MyBioSource
product type :
antibody
product name :
MMP11 antibody
catalog :
MBS9409414
quantity :
0.1 mL
price :
255 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Western blot analysis of extracts of various cell lines, using MMP11 antibody.
image 2 :
Immunohistochemistry analysis of paraffin-embedded human lung cancer tissue using MMP11 antibody.
product information
catalog number :
MBS9409414
products type :
Antibody
products full name :
MMP11 antibody
products short name :
[MMP11]
products name syn :
[ST3; SL-3; STMY3]
other names :
[stromelysin-3 preproprotein; Stromelysin-3; stromelysin-3; matrix metallopeptidase 11; Matrix metalloproteinase-11; MMP-11]
products gene name :
[MMP11]
other gene names :
[MMP11; MMP11; ST3; SL-3; STMY3; STMY3; SL-3; ST3; MMP-11]
uniprot entry name :
MMP11_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
488
specificity :
The antibody detects endogenous level of total MMP11 antibody.
purity :
Antibodies were purified by affinity purification using immunogen.
form :
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1.0 mg/ml
storage stability :
Store at -20°C
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western blotting: 1:500 - 1:2000. Immunohistochemistry: 1:50 - 1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen Type: Peptide. Immunogen Description: A synthetic peptide of human MMP11. SDS-PAGE MW: 55kD
other info2 :
Target Name: MMP11
products categories :
Total protein Ab
products description :
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.
ncbi gi num :
58331148
ncbi acc num :
NP_005931.2
ncbi gb acc num :
NM_005940.3
uniprot acc num :
P24347
ncbi pathways :
Activation Of Matrix Metalloproteinases Pathway (1270258); Collagen Degradation Pathway (1270259); Degradation Of The Extracellular Matrix Pathway (1270257); Extracellular Matrix Organization Pathway (1270244); Matrix Metalloproteinases Pathway (198900)
ncbi summary :
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]
uniprot summary :
MMP11: May play an important role in the progression of epithelial malignancies. Belongs to the peptidase M10A family. Protein type: EC 3.4.24.-; Secreted, signal peptide; Secreted; Extracellular matrix; Protease. Chromosomal Location of Human Ortholog: 22q11.23. Cellular Component: proteinaceous extracellular matrix; Golgi lumen; extracellular region. Molecular Function: zinc ion binding; metalloendopeptidase activity; calcium ion binding. Biological Process: collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; collagen fibril organization; multicellular organismal development; negative regulation of fat cell differentiation; proteolysis
size1 :
0.1 mL
price1 :
255 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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