product summary
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company name :
MyBioSource
product type :
antibody
product name :
NRP2 Antibody
catalog :
MBS9409047
quantity :
0.1 mL
price :
255 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Western blot analysis of extracts of various cell lines, using NRP2 antibody.
image 2 :
Immunohistochemistry of paraffin-embedded rat lung using NRP2 antibody at dilution of 1:200 (x400 lens)
product information
catalog number :
MBS9409047
products type :
Antibody
products full name :
NRP2 Antibody
products short name :
[NRP2]
products name syn :
[NP2; NPN2; PRO2714; VEGF165R2]
other names :
[neuropilin-2 isoform 2; Neuropilin-2; neuropilin-2; neuropilin 2; Vascular endothelial cell growth factor 165 receptor 2]
products gene name :
[NRP2]
other gene names :
[NRP2; NRP2; NP2; NPN2; PRO2714; VEGF165R2; VEGF165R2]
uniprot entry name :
NRP2_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
926
specificity :
The antibody detects endogenous level of total NRP2 protein.
purity :
Antibodies were purified by affinity purification using immunogen.
form :
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1.0 mg/ml
storage stability :
Store at -20°C
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western blotting: 1:500 - 1:2000. Immunohistochemistry: 1:50 - 1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen Type: Recombinant Protein. Immunogen Description: Recombinant protein of human NRP2. SDS-PAGE MW: 104 kD
other info2 :
Target Name: NRP2
products categories :
Total protein Ab
products description :
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
ncbi gi num :
41872533
ncbi acc num :
NP_003863.2
ncbi gb acc num :
NM_003872.2
uniprot acc num :
O60462
ncbi pathways :
Axon Guidance Pathway (1270303); Developmental Biology Pathway (1270302); L1CAM Interactions Pathway (1270323); Neurophilin Interactions With VEGF And VEGFR Pathway (1269486); NrCAM Interactions Pathway (1270329); Signal Transduction Pathway (1269379); Signaling By VEGF Pathway (1269480); Signaling Events Mediated By VEGFR1 And VEGFR2 Pathway (137940); VEGFR1 Specific Signals Pathway (137924)
ncbi summary :
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
NRP2: High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. Heterodimer with NRP1. Binds PLXNB1. Belongs to the neuropilin family. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; Receptor, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 2q33.3. Cellular Component: membrane; plasma membrane; integral to membrane; extracellular region. Molecular Function: heparin binding; vascular endothelial growth factor receptor activity; semaphorin receptor activity; metal ion binding; cytokine binding; growth factor binding; receptor activity. Biological Process: axon extension involved in axon guidance; axon guidance; positive regulation of endothelial cell proliferation; nerve development; angiogenesis; vascular endothelial growth factor receptor signaling pathway; cell adhesion
size1 :
0.1 mL
price1 :
255 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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