product summary
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company name :
MyBioSource
product type :
antibody
product name :
SLPI Antibody
catalog :
MBS9408899
quantity :
0.1 mL
price :
320 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS9408899 image 1
Western blot analysis of SLPI in A-20 cell lysate with SLPI antibody at 2 ug/mL.
product information
catalog number :
MBS9408899
products type :
Antibody
products full name :
SLPI Antibody
products short name :
[SLPI]
products name syn :
[mSLPI, Secretory leukocyte protease inhibitor, HUSI]
other names :
[antileukoproteinase; Antileukoproteinase; antileukoproteinase; secretory leukocyte peptidase inhibitor; Secretory leukocyte protease inhibitor]
products gene name :
[SLPI]
other gene names :
[Slpi; Slpi; ALP]
uniprot entry name :
SLPI_MOUSE
clonality :
Polyclonal
host :
Rabbit
reactivity :
Mouse
sequence length :
131
purity :
Affinity chromatography purified via peptide column
form :
Supplied in PBS containing 0.02% sodium azide.
concentration :
1mg/ml
storage stability :
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB)
image1 heading :
Western Blot (WB)
other info1 :
Immunogen Type: Peptide. Immunogen Description: Raised against a 17 amino acid peptide from near the center of mouse SLPI.
other info2 :
Target Name: SLPI
products categories :
Total protein Ab
products description :
Secretory leukocyte protease inhibitor (SLPI) is produced at mucosal surfaces, primarily the upper respiratory tract and is thought to play an important role in the antiprotease defense mechanism of the lung. SLPI forms inhibitory complexes with numerous proteolytic enzymes such as neutrophil elastase, and has been shown to possess anti-inflammatory, anti-viral, and antibacterial activities. Its expression in oral epithelial cells is stimulated by HIV-1 gp120, suggesting that SLPI is a component of the oral mucosal response to HIV-1. In peripheral blood monocytes, SLPI can inhibit NF-kB activation by inhibiting IkB degradation in the cytoplasm and competing for NF-kB binding sites in the nucleus. This attenuation of the inflammatory response may also act to suppress liver metastases and other cancer cell invasions, but promote blood-borne metastasis via an invasion-independent pathway.
ncbi gi num :
6755574
ncbi acc num :
NP_035544
ncbi gb acc num :
NM_011414.3
ncbi mol weight :
14,308 Da
uniprot summary :
SLPI: Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. May prevent elastase-mediated damage to oral and possibly other mucosal tissues. Protein type: Inhibitor; Secreted; Secreted, signal peptide. Cellular Component: extracellular matrix; extracellular region. Molecular Function: serine-type endopeptidase inhibitor activity; enzyme binding; protease inhibitor activity; endopeptidase inhibitor activity. Biological Process: negative regulation of viral genome replication; negative regulation of peptidase activity; negative regulation of protein binding
size1 :
0.1 mL
price1 :
320 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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