product summary
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company name :
MyBioSource
product type :
antibody
product name :
ECRG4 Antibody
catalog :
MBS9408781
quantity :
0.1 mL
price :
320 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
more info or order :
image
image 1 :
MyBioSource MBS9408781 image 1
Western blot analysis of ECRG4 in HeLa cell lysate with ECRG4 antibody at (A) 1 and (B) 2 ug/mL.
product information
catalog number :
MBS9408781
products type :
Antibody
products full name :
ECRG4 Antibody
products short name :
[ECRG4]
products name syn :
[Esophageal cancer-related gene 4 protein, Augurin, C2orf40]
other names :
[Esophagus cancer-related gene-2; Serine protease inhibitor Kazal-type 7; serine protease inhibitor Kazal-type 7; serine peptidase inhibitor, Kazal type 7 (putative); Esophagus cancer-related gene 2 protein; ECRG-2]
products gene name :
[ECRG4]
other gene names :
[SPINK7; SPINK7; ECG2; ECRG2; ECG2; ECRG-2]
uniprot entry name :
ISK7_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
85
specificity :
ECRG4 antibody is predicted to not cross-react with other ECRG family members.
purity :
Affinity chromatography purified via peptide column
form :
Supplied in PBS containing 0.02% sodium azide.
concentration :
1 mg/mL
storage stability :
Can be stored at -20°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB)
image1 heading :
Western Blot (WB)
other info1 :
Immunogen Type: Peptide. Immunogen Description: Raised against a 20 amino acid peptide near the carboxy terminus of human ECRG4.
other info2 :
Target Name: ECRG4
products categories :
Total protein Ab
products description :
The esophageal cancer-related gene 4 (ECRG4), also known as Augurin, was identified through differential display screening between esophageal cancer and normal tissue. Hypermethylation of CpG sites in the ECRG4 promoter correlate with ECRG4 downregulation in numerous esophageal squamous cell carcinoma tissues. In transfected cells, overexpression of ECRG4 induced G1 arrest, dephosphorylation of Rb and decreased expression of cyclins D1 and D3. Increased expression of ECRG4 in aged mouse brain is observed compared with young mouse brain. The increased ECRG4 level was accompanied by elevated senescence-associated acidic beta-galactosidase activity, suggesting that ECRG4 is involved in cellular differentiation and senescence.
ncbi gi num :
81097792
ncbi acc num :
AAI09386
uniprot summary :
SPINK7: Probable serine protease inhibitor. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 5q32. Cellular Component: extracellular region. Molecular Function: serine-type endopeptidase inhibitor activity; protein binding
size1 :
0.1 mL
price1 :
320 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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