catalog number :
MBS9408381
products full name :
TIPARP Antibody
products short name :
[TIPARP]
products name syn :
[PARP7; ARTD14; pART14]
other names :
[TCDD-inducible poly; TCDD-inducible poly [ADP-ribose] polymerase; TCDD-inducible poly [ADP-ribose] polymerase; TCDD-inducible poly(ADP-ribose) polymerase; ADP-ribosyltransferase diphtheria toxin-like 14; ARTD14; Poly [ADP-ribose] polymerase 7; PARP-7]
products gene name :
[TIPARP]
other gene names :
[TIPARP; TIPARP; PARP7; ARTD14; pART14; PARP7; ARTD14; PARP-7]
uniprot entry name :
PARPT_HUMAN
reactivity :
Human, Mouse
specificity :
The antibody detects endogenous levels of total TIPARP protein.
purity :
Antigen affinity purification.
form :
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
concentration :
2.9 mg/ml
storage stability :
Store at -20°C
tested application :
Western Blot (WB)
app notes :
Western blotting: 1:200-1:1000
image1 heading :
Testing Data
other info1 :
Immunogen Type: Peptide. Immunogen Description: Synthetic peptide corresponding to residues near the N terminal of human TCDD-inducible poly(ADP-ribose) polymerase
other info2 :
Target Name: TIPARP. SDS-PAGE MW: 76kD
products categories :
Total protein Ab
products description :
This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants.
ncbi acc num :
NP_001171646.1
ncbi gb acc num :
NM_001184717.1
ncbi summary :
This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
uniprot summary :
TIPARP: Poly [ADP-ribose] polymerase using NAD(+) as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. May play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals. Protein type: EC 2.4.2.30; Transferase. Chromosomal Location of Human Ortholog: 3q25.31. Cellular Component: nucleus. Molecular Function: metal ion binding; NAD+ ADP-ribosyltransferase activity. Biological Process: estrogen metabolic process; androgen metabolic process; platelet-derived growth factor receptor signaling pathway; palate development; multicellular organismal metabolic process; post-embryonic development; smooth muscle development; protein amino acid ADP-ribosylation; nitrogen compound metabolic process; skeletal morphogenesis; positive regulation of protein catabolic process; hemopoiesis; kidney development; vasculogenesis; female gonad development