catalog number :
MBS9408189
products full name :
DCAF7 antibody
products short name :
[DCAF7]
products name syn :
[AN11; HAN11; WDR68; SWAN-1]
other names :
[DDB1- and CUL4-associated factor 7; DDB1- and CUL4-associated factor 7; DDB1- and CUL4-associated factor 7; DDB1 and CUL4 associated factor 7; WD repeat-containing protein 68; WD repeat-containing protein An11 homolog]
products gene name :
[DCAF7]
other gene names :
[DCAF7; DCAF7; AN11; HAN11; WDR68; SWAN-1; HAN11; WDR68]
uniprot entry name :
DCAF7_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
The antibody detects endogenous level of total DCAF7 antibody.
purity :
Antibodies were purified by affinity purification using immunogen.
form :
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1.0 mg/ml
storage stability :
Store at -20 degree C
tested application :
Western Blot (WB), Immunofluorescence (IF)
app notes :
Western blotting: 1:500 - 1:2000. Immunofluorescence: 1:50 - 1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunofluorescence (IF)
other info1 :
Immunogen Type: Recombinant Protein. Immunogen Description: Recombinant protein of human DCAF7.
other info2 :
Target Name: DCAF7
products categories :
Total protein Ab
products description :
This gene encodes a protein with multiple WD40 repeats which facilitate protein-protein interactions and thereby enable the assembly of multiprotein complexes. This protein has been shown to function as a scaffold protein for protein complexes involved in kinase signaling. This highly conserved gene is present in eukaryotic plants, fungi, and animals. The ortholog of this gene was first identified in plants as a key regulator of anthocyanin biosynthesis and flower pigmentation. Alternative splicing results in multiple transcript variants.
ncbi acc num :
NP_005819.3
ncbi gb acc num :
NM_005828.4
ncbi pathways :
TNF-alpha/NF-kB Signaling Pathway (198884)
ncbi summary :
This gene encodes a protein with multiple WD40 repeats which facilitate protein-protein interactions and thereby enable the assembly of multiprotein complexes. This protein has been shown to function as a scaffold protein for protein complexes involved in kinase signaling. This highly conserved gene is present in eukaryotic plants, fungi, and animals. The ortholog of this gene was first identified in plants as a key regulator of anthocyanin biosynthesis and flower pigmentation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
uniprot summary :
WDR68: a WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Protein type: Unknown function. Chromosomal Location of Human Ortholog: 17q23.3. Cellular Component: nucleoplasm; nuclear matrix; protein complex; cytoplasm. Molecular Function: protein binding. Biological Process: multicellular organismal development; protein ubiquitination