product summary
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company name :
MyBioSource
product type :
antibody
product name :
DGAT2 antibody
catalog :
MBS9407865
quantity :
0.1 mL
price :
320 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
more info or order :
image
image 1 :
Western Blot analysis DGAT2 using K562 whole cell lysates
product information
catalog number :
MBS9407865
products type :
Antibody
products full name :
DGAT2 antibody
products short name :
[DGAT2]
other names :
[diacylglycerol O-acyltransferase 2 isoform 1; Diacylglycerol O-acyltransferase 2; diacylglycerol O-acyltransferase 2; diacylglycerol O-acyltransferase 2; Acyl-CoA retinol O-fatty-acyltransferase (EC:2.3.1.76); ARAT; Retinol O-fatty-acyltransferase; Diglyceride acyltransferase 2]
products gene name :
[DGAT2]
other gene names :
[DGAT2; DGAT2; ARAT; HMFN1045; GS1999FULL; ARAT; Retinol O-fatty-acyltransferase]
uniprot entry name :
DGAT2_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
388
purity :
Purified by antigen-affinity chromatography.
form :
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
concentration :
1 mg/ml
storage stability :
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
tested application :
Western Blot (WB)
app notes :
Western blotting: 1:1000-1:3000
image1 heading :
Western Blot
other info1 :
Immunogen: A synthesized peptide derived from human DGAT2
other info2 :
Target Name: DGAT2
products categories :
Total protein Ab
products description :
Acyl-CoA: diacylglycerol acyltransferase, or DGAT (EC 2.3.1.20), is responsible for the synthesis of triglycerides. It catalyzes a reaction in which diacylglycerol is covalently joined to long chain fatty acyl-CoAs.[supplied by OMIM]
ncbi gi num :
26024197
ncbi acc num :
NP_115953
ncbi gb acc num :
NM_032564.4
ncbi mol weight :
44kd
ncbi pathways :
Acyl Chain Remodeling Of DAG And TAG Pathway (1270056); Fat Digestion And Absorption Pathway (194385); Fat Digestion And Absorption Pathway (194324); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (1270010); Glycerolipid Metabolism Pathway (82986); Glycerolipid Metabolism Pathway (361); Glycerophospholipid Biosynthesis Pathway (1270054); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001)
ncbi summary :
This gene encodes one of two enzymes which catalyzes the final reaction in the synthesis of triglycerides in which diacylglycerol is covalently bound to long chain fatty acyl-CoAs. The encoded protein catalyzes this reaction at low concentrations of magnesium chloride while the other enzyme has high activity at high concentrations of magnesium chloride. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
uniprot summary :
DGAT2: Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides. Functions also as an acyl-CoA retinol acyltransferase (ARAT). Belongs to the diacylglycerol acyltransferase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 2.3.1.76; Membrane protein, multi-pass; Membrane protein, integral; Cofactor and Vitamin Metabolism - retinol; Lipid Metabolism - glycerolipid; Transferase; EC 2.3.1.20. Chromosomal Location of Human Ortholog: 11q13.5. Cellular Component: endoplasmic reticulum membrane; mitochondrion; perinuclear region of cytoplasm; endoplasmic reticulum; integral to membrane; integral to endoplasmic reticulum membrane; lipid particle. Molecular Function: 2-acylglycerol O-acyltransferase activity; protein homodimerization activity; retinol O-fatty-acyltransferase activity; diacylglycerol O-acyltransferase activity. Biological Process: cholesterol homeostasis; sequestering of lipid; retinol metabolic process; glycerol metabolic process; phospholipid metabolic process; fatty acid homeostasis; glycerophospholipid biosynthetic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; diacylglycerol metabolic process
size1 :
0.1 mL
price1 :
320 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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