catalog number :
MBS9407636
products full name :
C3AR1 Antibody
products short name :
[C3AR1]
products name syn :
[AZ3B; C3AR; HNFAG09]
other names :
[C3a anaphylatoxin chemotactic receptor; C3a anaphylatoxin chemotactic receptor; C3a anaphylatoxin chemotactic receptor; complement component 3a receptor 1]
products gene name :
[C3AR1]
other gene names :
[C3AR1; C3AR1; AZ3B; C3AR; HNFAG09; AZ3B; C3R1; HNFAG09; C3AR; C3a-R]
uniprot entry name :
C3AR_HUMAN
reactivity :
Human, Mouse
specificity :
The antibody detects endogenous levels of total C3AR1 protein.
purity :
Antigen affinity purification.
form :
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
storage stability :
Store at -20°C
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western blotting: 1:200-1:1000. Immunohistochemistry: 1:50-1:200
image1 heading :
Testing Data
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen Type: Recombinant Protein. Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human complement component 3a receptor 1. SDS PAGE MW: 54Kd
other info2 :
Target Name: C3AR1
products categories :
Total protein Ab
products description :
The C3a receptor also known as complement component 3a receptor 1 (C3AR1) is a G protein-coupled receptorprotein involved in the complement system. Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.
ncbi acc num :
NP_004045.1
ncbi gb acc num :
NM_004054.2
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); G Alpha (i) Signalling Events Pathway (1269576); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); GPCRs, Class A Rhodopsin-like Pathway (198886); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462)
uniprot summary :
C3aR: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR. Chromosomal Location of Human Ortholog: 12p13.31. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: G-protein coupled receptor activity; C3a anaphylatoxin receptor activity; complement component C3a receptor activity; phosphoinositide phospholipase C activity. Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; positive regulation of angiogenesis; metabolic process; blood circulation; complement receptor mediated signaling pathway; inflammatory response; chemotaxis