product summary
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company name :
MyBioSource
product type :
antibody
product name :
CHGA Antibody
catalog :
MBS9407527
quantity :
0.1 mL
price :
255 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Gel: 8%SDS-PAGE. Lysates (from left to right): A549 and 293T cell, human normal. kidney tissue and hela cell. Amount of lysate: 40ug per lane. Primary antibody: 1/200 dilution . Secondary antibody dilution: 1/8000. Exposure time: 1 minute
image 2 :
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/20.
product information
catalog number :
MBS9407527
products type :
Antibody
products full name :
CHGA Antibody
products short name :
[CHGA]
products name syn :
[CGA]
other names :
[chromogranin-A isoform 1 preproprotein; Chromogranin-A; chromogranin-A; chromogranin A; SL21]
products gene name :
[CHGA]
other gene names :
[CHGA; CHGA; CGA; CgA; SP-I]
uniprot entry name :
CMGA_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
sequence length :
457
specificity :
The antibody detects endogenous levels of total CHGA protein.
purity :
Antigen affinity purification.
form :
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
concentration :
1.2 mg/ml
storage stability :
Store at -20°C
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western blotting: 1:500-1:2000. Immunohistochemistry: 1:25-1:100
image1 heading :
Testing Data
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen Type: Peptide. Immunogen Description: Synthetic peptide of human chromogranin A (parathyroid secretory protein 1). SDS-PAGE MW: 51 kD
other info2 :
Target Name: CHGA
products categories :
Total protein Ab
products description :
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene.
ncbi gi num :
4502805
ncbi acc num :
NP_001266.1
ncbi gb acc num :
NM_001275.3
uniprot acc num :
P10645
ncbi summary :
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
uniprot summary :
CHGA: a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells and is a precursor to multiple biologically active peptides including vasostatin, pancreastatin, and chromostatin. Binds calcium with a low-affinity. Vasostatin negatively regulates angiogenesis and has antibacterial activity against some Gram-positive bacteria. Pancreastatin inhibits glucose induced insulin release from the pancreas. Chromostatin inhibits catecholamine release from chromaffin cells. Protein type: Cell adhesion; Vesicle; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 14q32. Cellular Component: perinuclear region of cytoplasm; extracellular region; secretory granule. Biological Process: regulation of blood pressure
size1 :
0.1 mL
price1 :
255 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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