product summary
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company name :
MyBioSource
product type :
antibody
product name :
Guanylate Cyclase beta Antibody
catalog :
MBS9407443
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
image
image 1 :
Western blot analysis of extracts from HuvEc cells, using Guanylate Cyclase b antibody.
image 2 :
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Guanylate Cyclase b antibody.
product information
catalog number :
MBS9407443
products type :
Antibody
products full name :
Guanylate Cyclase beta Antibody
products short name :
[Guanylate Cyclase beta]
products name syn :
[Guanylate Cyclase b Antibody; 4.6.1.2; GC-S-beta-1; GC-SB3; GUC1B3; GUCB3]
other names :
[guanylate cyclase soluble subunit beta-1 isoform 2; Guanylate cyclase soluble subunit beta-1; guanylate cyclase soluble subunit beta-1; guanylate cyclase 1, soluble, beta 3; Guanylate cyclase soluble subunit beta-3; GCS-beta-3; Soluble guanylate cyclase small subunit]
other gene names :
[GUCY1B3; GUCY1B3; GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B1; GC-S-beta-1; GUC1B3; GUCSB3; GUCY1B1; GCS-beta-1; GCS-beta-3]
uniprot entry name :
GCYB1_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
619
specificity :
The antibody detects endogenous levels of total Guanylate Cyclase b protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1.0 mg/ml
storage stability :
Store at -20°C
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
Western blotting: 1:500~1:3000. Immunohistochemistry: 1:50~1:100
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen Type: Peptide. Immunogen Description: Synthesized peptide derived from human Guanylate Cyclase b. SDS-PAGE MW: 70 kD
other info2 :
Target Name: Guanylate Cyclase b
products categories :
Total protein Ab
products description :
This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.A. Shimouchi, Am J Physiol Lung Cell Mol Physiol, Nov 1993; 265: 456.Peter Sinnaeve, Circ. Res., Jan 2001; 88: 103.Stephan Thelitz, J. Thorac. Cardiovasc. Surg., May 2004; 127: 1285 - 1292.Richard C. Venema, Am J Physiol Heart Circ Physiol, Jul 2003; 2
ncbi gi num :
4504215
ncbi acc num :
NP_000848.1
ncbi gb acc num :
NM_000857.3
uniprot acc num :
Q02153
ncbi pathways :
Circadian Entrainment Pathway (698773); Circadian Entrainment Pathway (699872); Gap Junction Pathway (83072); Gap Junction Pathway (483); Hemostasis Pathway (1269340); Long-term Depression Pathway (83086); Long-term Depression Pathway (497); Nitric Oxide Stimulates Guanylate Cyclase Pathway (1269343); Oxytocin Signaling Pathway (952859); Oxytocin Signaling Pathway (960764)
ncbi summary :
This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
uniprot summary :
GUCY1B3: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Heterodimer of an alpha and a beta chain. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Guanylyl cyclase; Nucleotide Metabolism - purine; Lyase; EC 4.6.1.2; Receptor, misc. Chromosomal Location of Human Ortholog: 4q31.3-q33. Cellular Component: guanylate cyclase complex, soluble; intracellular membrane-bound organelle; cytoplasm. Molecular Function: guanylate cyclase activity; GTP binding; protein heterodimerization activity; metal ion binding; heme binding; Hsp90 protein binding; receptor activity. Biological Process: cGMP biosynthetic process; blood circulation; blood coagulation; nitric oxide mediated signal transduction
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
255
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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